UC

Contacto

Dra. Luz OPPLIGER

comunicaciones@bio.puc.cl

FISIOLOGÍA

OWEN ,GARETH IVOR

Gareth Ivor Owen Gareth Ivor Owen

Laboratorio: 6862854
Mail: Esta dirección de correo electrónico está protegida contra spambots. Usted necesita tener Javascript activado para poder verla.


Profesor Asociado

Unidad de Endocrinología y Reproducción

FISIOLOGÍA,
Facultad de Ciencias Biológicas,
Pontificia Universidad Católica de Chile, Alameda 340, Santiago

Antecedentes Académicos

Endocrinología, University of Colorado (1998).
Doctor, University of London (1996).
Licenciado, King's College London (1992).

Postdoctorado:

University of Colorado, USA, (1996-1998) Postdoctorado. Institute of Cancer Research, London, UK, (1998 -2000)

Especialización:

Investigación en cáncer de ovario y mama y endocrinología en reproducción.

Actividades de Docencia

Pregado
  • 2018 BIO305E-1, Aspectos Básicos Y Clínicos De Cáncer.
  • 2017 BIO135N-1, Fisiología.
  • 2017 BIO305E-1, Aspectos Básicos Y Clínicos De Cáncer.
Postgrado
  • 2018 BIO4029-1, Señalización En El Desarrollo.
  • 2017 BIO4029-1, Señalización En El Desarrollo.
  • 2017 BIO4029-1, Señalización En El Desarrollo.

Líneas de Investigación

Estamos desarrollando ensayos diagnósticos moleculares y celulares para seleccionar tratamientos a medida para pacientes de cáncer. Nuestro objetivo es establecer una técnica rápida para evaluar la respuesta a la quimioterapia y los tratamientos alternativos del cáncer en los tumores individuales. Además, tenemos previsto buscar y validar los transcritos de ARNm que han alterado los patrones de expresión en los tumores, con el fin de utilizar patrones tales como marcadores predictivos en la respuesta del paciente y el pronóstico. Otras áreas de investigación incorporan el desarrollo de nuevos fármacos antiangiogénicos y la investigación del papel del sistema de coagulación en la metástasis del cáncer. La investigación en la reproducción humana se centra en el papel de la FSH y de unión a carbohidratos en el proceso de atresia folicular.


Titulo: Estudio De La Relación Entre Los Parámetros De Difusión Obtenidos Mediante Imágenes De Resonancia Magnética (Dwrm) Y El Número De Células Clonogénicas En Un Tumor O Muestra
Año: 2016
Concurso e institución: Interdisciplina, UC
Investigador principal: Sanchez Nieto Beatriz
Otros investigadores: Sanchez Nieto Beatriz, Owen Gareth Ivor
Fecha inicio: 01-08-2016
Fecha termino: 01-07-2018
Duración: 23 meses

Titulo: Modulation Of The Process Of Angiogenesis By Coagulation Factor X
Año: 2014
Concurso e institución: Regular, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Cuello Fredes Mauricio Arturo, Velasquez Opazo Ethel, Valenzuela Bassi Rodrigo Andres
Fecha inicio: 01-03-2014
Fecha termino: 01-03-2018
Duración: 48 meses

Titulo: Advanced Center For Chronic Diseases (Accdis)
Año: 2014
Concurso e institución: Apoyo A La Investigación En Centros De Excelencia, CONICYT
Investigador principal: Lavandero Gonzlez Sergio
Otros investigadores: Lavandero Gonzlez Sergio, Owen Gareth Ivor
Fecha inicio: 01-01-2014
Fecha termino: 01-01-2024
Duración: 120 meses

Titulo: Predicción De Respuesta A Quimioterapia Para Cáncer
Año: 2013
Concurso e institución: I+D Precompetitiva, CORFO
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Cuello Fredes Mauricio Arturo
Fecha inicio: 01-11-2013
Fecha termino: 01-11-2015
Duración: 24 meses

Titulo: Desarrollo De Un Ensayo "in Vitro" Para Establecer El Uso De Medicina Personalizada En Pacientes Con Cancer De Ovario
Año: 2011
Concurso e institución: Postdoctorado, CONICYT
Investigador principal: Bravo Castillo Maria Loreto
Otros investigadores: Bravo Castillo Maria Loreto, Owen Gareth Ivor
Fecha inicio: 01-10-2011
Fecha termino: 01-10-2014
Duración: 36 meses

Titulo: The Identification Of Subgroups Of Obese Womenwith Differing Potential Risk For Developing Endometrial Carcinoma
Año: 2011
Concurso e institución: Regular, CONICYT
Investigador principal: Villavicencio Alejandra
Otros investigadores: Villavicencio Alejandra, Owen Gareth Ivor
Fecha inicio: 01-03-2011
Fecha termino: 01-03-2015
Duración: 48 meses

Titulo: Generacion Y Desarrollo De Nuevos Farmacos Para El Tratamiento De Canceres Dependientes Del Egfr
Año: 2010
Concurso e institución: Investigación Y Desarrollo, CONICYT
Investigador principal: Gonzalez Alfonso
Otros investigadores: Gonzalez Alfonso, Owen Gareth Ivor
Fecha inicio: 01-03-2010
Fecha termino: 01-03-2013
Duración: 36 meses

Titulo: Primary Aldosteronism And Hsd11B2 Enzyme Activity Defects In Pediatric Population And Its Impact On The Generation Of Endothelial Injury, Oxidative Stress And Arterial Hypertension
Año: 2010
Concurso e institución: Regular, CONICYT
Investigador principal: Fardella Bello Carlos Enrique
Otros investigadores: Fardella Bello Carlos Enrique, Campino Johnson Maria Del Carmen, Martinez Aguayo Alejandro Gregorio, Garcia Bruce Hernan Gabriel, Aglony Imbarack Marlene Elizabeth, Owen Gareth Ivor
Fecha inicio: 01-03-2010
Fecha termino: 01-03-2013
Duración: 36 meses

Titulo: Study Of A Novel Human Follicle Stimulating Hormone (Fsh) Variant: Elucidation Of The Physiological Role And Pathological Implications
Año: 2010
Concurso e institución: Regular, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Cuello Fredes Mauricio Arturo, Villalon Bravo Manuel Jose
Fecha inicio: 01-03-2010
Fecha termino: 01-03-2014
Duración: 48 meses

Titulo: Consorcio Tecnológico En Biomedicina Aplicada Para El Desarrollo De Nuevas Estrategias De Prevención, Diagnóstico Y Tratamiento De Enfermedades Humanas
Año: 2008
Concurso e institución: , CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Cuello Fredes Mauricio Arturo
Fecha inicio: 01-07-2008
Fecha termino: 01-10-2013
Duración: 63 meses

Titulo: Elucidation Of The Regulation And Pathophysiological Actions Of Tissue Factor In Breast And Endometrial Cancer
Año: 2008
Concurso e institución: Incentivo A La Cooperación Internacional, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor
Fecha inicio: 01-06-2008
Fecha termino: 01-06-2009
Duración: 12 meses

Titulo: Efectos De Las Estatinas En La Capacidad Metastásica Y La Sensibilidad A Agentes Inductores De Apoptosisi En El Cáncer De Ovario
Año: 2008
Concurso e institución: Regular, CONICYT
Investigador principal: Cuello Fredes Mauricio Arturo
Otros investigadores: Cuello Fredes Mauricio Arturo, Branes Yunusic Jorge Antonio, Gejman Enriquez Roger, Kato Cardemil Sumie Rode, Owen Gareth Ivor
Fecha inicio: 01-03-2008
Fecha termino: 01-03-2012
Duración: 48 meses

Titulo: Desarrollo De Kits Inmunocromatográficos Rápidos Para La Detección De Virus Respiratorios De Importancia En Salud Pública
Año: 2008
Concurso e institución: Investigación Y Desarrollo, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor
Fecha inicio: 01-01-2008
Fecha termino: 01-01-2011
Duración: 36 meses

Titulo: Evaluacion Clinico-Molecular Del Rol De Las Deshidrogenasas Tipo 1 Y 2 (11Bhsd1 Y 11Bhsd2) En La Genesis De La Hipertension Arterial Hiporrennemica
Año: 2007
Concurso e institución: Regular, CONICYT
Investigador principal: Fardella Bello Carlos Enrique
Otros investigadores: Fardella Bello Carlos Enrique, Carvajal Maldonado Cristian Andres, Mosso Gomez Lorena Montserrat, Owen Gareth Ivor
Fecha inicio: 01-03-2007
Fecha termino: 01-03-2010
Duración: 36 meses

Titulo: Elucidation Of The Regulation And Pathophysiological Actions Of Tissue Factor In Breast And Endometrial Cancer
Año: 2006
Concurso e institución: Regular, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Villalon Bravo Manuel Jose
Fecha inicio: 01-03-2006
Fecha termino: 01-03-2010
Duración: 48 meses

Titulo: Papel Parodójico De La Progesterona En La Mama Y El Endometrio Uterino: Elucidación De La "cross-Talk" Entre La Progesterona Y La Vía De Señal Del Egf
Año: 2002
Concurso e institución: Regular, CONICYT
Investigador principal: Owen Gareth Ivor
Otros investigadores: Owen Gareth Ivor, Villalon Bravo Manuel Jose
Fecha inicio: 01-03-2002
Fecha termino: 01-03-2006
Duración: 48 meses


Publicaciones ISI

1
Angiogenesis Inhibitors In Early Development For Gastric Cancer
Autor(es): Pinto M, Owen G, Retamal I , Garrido M
Año: 2017.26:1007-1017.
Ref: Pinto M, Owen G, Retamal I , Garrido M . Angiogenesis inhibitors in early development for gastric cancer. Expert Opinion On Investigational Drugs. 2017;26(9):1007-1017.

2
Venlafaxine Treatment After Endothelin-1-Induced Cortical Stroke Modulates Growth Factor Expression And Reduces Tissue Damage In Rats
Autor(es): Rodrigo Zepeda, Valentina Contreras, Claudia Pissani, Katherine Stack, Macarena Vargas, Gareth I Owen, Oscar M Lazo, Francisca C Bronfman
Año: 2016.1:131-145.
Ref: Rodrigo Zepeda, Valentina Contreras, Claudia Pissani, Katherine Stack, Macarena Vargas, Gareth I Owen, Oscar M Lazo, Francisca C Bronfman. Venlafaxine treatment after endothelin-1-induced cortical stroke modulates growth factor expression and reduces tissue damage in rats. Neuropharmacology. 2016;1(107):131-145.

3
Modulatory Effect Of 2-(4-Hydroxyphenyl)Amino-1,4-Naphthoquinone On Endothelial Vasodilation In Rat Aorta
Autor(es): Javier Palacios, Fredi Cifuentes, Jaime Valderrama, Julio Benites, David Rios, Constanza Gonzalez, Mario Chiong, Benjamin Cartes-Saavedra, Carlos Lafourcade, Ursula Wyneken, Pamela Gonzalez, Gareth I Owen, Fabian Pardo, Luis Sobrevia, Pedro Buc Calderon
Año: 2016.2016:1-12.
Ref: Javier Palacios, Fredi Cifuentes, Jaime Valderrama, Julio Benites, David Ríos, Constanza González, Mario Chiong, Benjamín Cartes-Saavedra, Carlos Lafourcade, Ursula Wyneken, Pamela González, Gareth I Owen, Fabián Pardo, Luis Sobrevia, Pedro Buc Calderon. Modulatory effect of 2-(4-hydroxyphenyl)amino-1,4-naphthoquinone on endothelial vasodilation in rat aorta. Oxidative Medicine and Cellular Longevity . 2016;2016(2016):1-12.

4
Citosine-Adenine-Repeat Microsatellite Of 11β-Hydroxysteroid Dehydrogenase 2 Gene In Hypertensive Children
Autor(es): Carolina Valdivia, Cristian A. Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F. Lagos, Alejandra Tapia-Castillo, Cristobal A. Fuentes, Marlene Aglony, Sandra Solari, Alexis M. Kalergis, Hernan Garcia, Gareth I. Owen, Carlos E. Fardella
Año: 2016.29:25-32.10.1093/ajh/hpv052
Ref: Carolina Valdivia, Cristian A. Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F. Lagos, Alejandra Tapia-Castillo, Cristobal A. Fuentes, Marlene Aglony, Sandra Solari, Alexis M. Kalergis, Hernan García, Gareth I. Owen, Carlos E. Fardella. Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children. American Journal Of Hypertension. 2016;29(1):25-32.

5
Escaping Antiangiogenic Therapy: Strategies Employed By Cancer Cells
Autor(es): Mauricio P Pinto, Paula Sotomayor, Gonzalo Carrasco-Avino, Alejandro H Corvalan, Gareth I Owen
Año: 2016.9:1489-1509.doi: 10.3390/ijms17091489
Ref: Mauricio P Pinto, Paula Sotomayor, Gonzalo Carrasco-Avino, Alejandro H Corvalan, Gareth I Owen. Escaping antiangiogenic therapy: strategies employed by cancer cells. International Journal Of Molecular Sciences. 2016;9(17):1489-1509.

6
Evolutionary History Of The Reprimo Tumor Suppressor Gene Family In Vertebrates With A Description Of A New Reprimo Gene Lineage
Autor(es): Wichmann I, Zavala K, Hoffmann F, Vandewege M, Corvalan A, Amigo J, Owen G, Opazo J
Año: 2016.591:245-254.
Ref: Wichmann I, Zavala K, Hoffmann F, Vandewege M, Corvalan A, Amigo J, Owen G, Opazo J. Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage. Gene. 2016;591(1):245-254.

7
Citosine-Adenine-Repeat Micrisatellite Of 11B-Hydroxysteroid Dehydrogensase 2 Gene In Hypertensive Children
Autor(es): Cristian Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Sandra Solari, Alexis Kalergis, Hernan Garcia, Gareth Owen, Carlos Fardella
Año: 2016.29:25-32.10.1093/ajh/hpv052
Ref: Cristian Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Sandra Solari, Alexis Kalergis, Hernan Garcia, Gareth Owen, Carlos Fardella. Citosine-Adenine-Repeat Micrisatellite of 11b-hydroxysteroid dehydrogensase 2 gene in hypertensive children. American Journal Of Hypertension. 2016;29(1):25-32.

8
Leptin Stimulates Migration And Invasion And Maintains Cancer Stem-Like Properties In Ovarian Cancer Cells: An Explanation For Poor Outcomes In Obese Women
Autor(es): Sumie Kato, Lorena Abarzua-Catalan, Cesar Trigo, Ana Delpiano, Cristobal Sanhueza, Karen Garcia, Carolina Ibanez, Katherine Hormazabal, Daniela Diaz, Jorge Branes, Enrique Castellon, Erasmo Bravo, Gareth Owen, Mauricio Cuello
Año: 2015.25:21100-21119.10.18632/oncotarget.4228
Ref: Sumie Kato, Lorena Abarzua-Catalan, Cesar Trigo, Ana Delpiano, Cristobal Sanhueza, Karen Garcia, Carolina Ibañez, Katherine Hormazabal, Daniela Diaz, Jorge Brañes, Enrique Castellón, Erasmo Bravo, Gareth Owen, Mauricio Cuello. Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women. Oncotarget. 2015;25(6):21100-21119.

9
The Twisted Survivin Connection To Angiogenesis
Autor(es): Sanhueza C, Wehinger S, Bennett J, Valenzuela M, Owen G, Quest A
Año: 2015.14:1-15.
Ref: Sanhueza C, Wehinger S, Bennett J, Valenzuela M, Owen G, Quest A. The twisted survivin connection to angiogenesis. Molecular Cancer. 2015;14(198):1-15.

10
Platelets Enhance Tissue Factor Protein And Metastasis Initiating Cell Markers, And Act As Chemoattractants Increasing The Migration Of Ovarian Cancer Cells
Autor(es): Renan Orellana, Sumie Kato, Rafaela Erices, Maria Loreto Bravo, Pamela Gonzalez, Barbara Oliva, Sofia Cubillos, Andres Valdivia, Carolina Ibanez, Jorge Branes, Maria Isabel Barriga, Erasmo Bravo, Catalina Alonso, Eva Bustamante, Enrique Castellon, Patricia Hidalgo, Cesar Trigo, Olga Panes, Jaime Pereira, Diego Mezzano, Mauricio A Cuello, Gareth I Owen
Año: 2015.1:290-305.10.1186/s12885-015-1304-z
Ref: Renan Orellana, Sumie Kato, Rafaela Erices, Maria Loreto Bravo, Pamela González, Barbara Oliva, Sofia Cubillos, Andrés Valdivia, Carolina Ibañez, Jorge Brañes, Maria Isabel Barriga, Erasmo Bravo, Catalina Alonso, Eva Bustamante, Enrique Castellon, Patricia Hidalgo, Cesar Trigo, Olga Panes, Jaime Pereira, Diego Mezzano, Mauricio A Cuello, Gareth I Owen. Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells. Bmc Cancer. 2015;1(15):290-305.

11
Enhanced Caveolin-1 Expression Increases Migration, Anchorage-Independent Growth And Invasion Of Endometrial Adenocarcinoma Cells
Autor(es): Natalia Diaz-Valdivia, Denisse Bravo, Hernan Huerta, Soledad Henriquez, Fernando Gabler, Margarita Vega, Carmen Romero, Claudia Calderon, Gareth I. Owen, Lisette Leyton, Andrew F. G. Quest
Año: 2015.15:463-474.10.1186/s12885-015-1477-5
Ref: Natalia Diaz-Valdivia, Denisse Bravo, Hernán Huerta, Soledad Henriquez, Fernando Gabler, Margarita Vega, Carmen Romero, Claudia Calderón, Gareth I. Owen, Lisette Leyton, Andrew F. G. Quest. Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells. Bmc Cancer. 2015;15(10):463-474.

12
Progesterone Regulation Of Tissue Factor Depends On Mek1/2 Activation And Requires The Proline-Rich Site On Progesterone Receptor
Autor(es): Maria Loreto Bravo, Mauricio P. Pinto, Ibeth Gonzalez, Barbara Oliva, Sumie Kato, Mauricio A. Cuello, Carol A. Lange, Gareth I. Owen
Año: 2015.1:309-320.10.1007/s12020-014-0288-9
Ref: María Loreto Bravo, Mauricio P. Pinto, Ibeth González, Barbara Oliva, Sumie Kato, Mauricio A. Cuello, Carol A. Lange, Gareth I. Owen. Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor. Endocrine. 2015;1(48):309-320.

13
A Snapshot Of Cancer In Chile: Analytical Frameworks For Developing A Cancer Policy
Autor(es): Jorge Jimenez De La Jara, Gabriel Bastias, Catterina Ferreccio, Cristian Moscoso, Sofia Sagues, Camilo Cid, Eduardo Bronstein, Cristian Herrera, Bruno Nervi, Alejandro Corvalan, Ethel Velasquez, Pamela Gonzalez, Enrique Castellon, Eva Bustamante, Sergio Onate, Eileen Mcnerney, Richard Sullivan, Gareth I. Owen
Año: 2015.1:1-10.10.1186/0717-6287-48-10.
Ref: Jorge Jimenez de la Jara, Gabriel Bastias, Catterina Ferreccio, Cristian Moscoso, Sofia Sagues, Camilo Cid, Eduardo Bronstein, Cristian Herrera, Bruno Nervi, Alejandro Corvalan, Ethel Velasquez, Pamela González, Enrique Castellón, Eva Bustamante, Sergio Oñate, Eileen McNerney, Richard Sullivan, Gareth I. Owen. A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy. Biological Research. 2015;1(48):1-10.

14
2-Methoxyestradiol And Disorders Of Female Reproductive Tissues
Autor(es): Pinto M, Owen G, Medina R
Año: 2014.5:274-283.
Ref: Pinto M, Owen G, Medina R. 2-Methoxyestradiol and Disorders of Female Reproductive Tissues. Hormones And Cancer. 2014;5(5):274-283.

15
Identification Of Novel 11 Beta-Hsd1 Inhibitors By Combined Ligand- And Structure-Based Virtual Screening
Autor(es): Lagos C, Vecchiola A, Allende F, Fuentes C, Tichauer J, Valdivia C, Solari S, Campino C, Tapia-Castillo A, Baudrand R, Villarroel P, Cifuentes M, Owen G, Carvajal C, Fardella C
Año: 2014.384:71-82.
Ref: Lagos C, Vecchiola A, Allende F, Fuentes C, Tichauer J, Valdivia C, Solari S, Campino C, Tapia-Castillo A, Baudrand R, Villarroel P, Cifuentes M, Owen G, Carvajal C, Fardella C. Identification of novel 11 beta-HSD1 inhibitors by combined ligand- and structure-based virtual screening. Molecular And Cellular Endocrinology. 2014;384(1-2):71-82.

16
Lc-Ms/ms Method For The Simultaneous Determination Of Free Urinary Steroids
Autor(es): Allende F, Solari S, Campino C, Carvajal C, Lagos C, Vecchiola A , Valdivia C, Baudrand R, Owen G, Fardella C
Año: 2014.77:637-642.
Ref: Allende F, Solari S, Campino C, Carvajal C, Lagos C, Vecchiola A , Valdivia C, Baudrand R, Owen G, Fardella C. LC-MS/MS method for the simultaneous determination of free urinary steroids. Chromatographia. 2014;77(7-8):637-642.

17
High Sodium Intake Is Associated With Increased Glucocorticoid Production, Insulin Resistance And Metabolic Syndrome
Autor(es): Baudrand R, Campino C, Carvajal C, Olivieri O, Guidi G, Faccini G, Voehringer P, Cerda J, Owen G, Kalergis A, Fardella C
Año: 2014.80:677-684.
Ref: Baudrand R, Campino C, Carvajal C, Olivieri O, Guidi G, Faccini G, Voehringer P, Cerda J, Owen G, Kalergis A, Fardella C. High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome. Clinical Endocrinology. 2014;80(5):677-684.

18
Independent Anti-Angiogenic Capacities Of Coagulation Factors X And Xa
Autor(es): Lange S, Gonzalez I, Pinto M, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henriquez S, Velasquez E, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo K, Kalergis A, Pererira K, Mendoza C, Saez C, Kato S, Cuello M, Parborell F, Irusta G, Palma V, Allende M, Owen G
Año: 2014.229:1673-1680.
Ref: Lange S, Gonzalez I, Pinto M, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henríquez S, Velasquez E, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo K, Kalergis A, Pererira K, Mendoza C, Saez C, Kato S, Cuello M, Parborell F, Irusta G, Palma V, Allende M, Owen G. Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa. Journal Of Cellular Physiology. 2014;229(11):1673-1680.

19
Metformin, At Concentrations Corresponding To The Treatment Of Diabetes, Potentiates The Cytotoxic Effects Of Carboplatin In Cultures Of Ovarian Cancer Cells
Autor(es): Erices R, Bravo Ml, Gonzalez P, Oliva B, Racordon D, Garrido M, Ibanez C, Kato S, Branes J, Pizarro J, Barriga Mi, Barra A, Bravo E, Alonso C, Bustamante E, Cuello Ma, Owen Gi
Año: 2013.12:1433-1446.10.1177/1933719113488441
Ref: Erices R, Bravo ML, Gonzalez P, Oliva B, Racordon D, Garrido M, Ibañez C, Kato S, Brañes J, Pizarro J, Barriga MI, Barra A, Bravo E, Alonso C, Bustamante E, Cuello MA, Owen GI. Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells. Reproductive Sciences. 2013;12(20):1433-1446.

20
Antiangiogenic, Antimigratory And Antiinflammatory Effects Of 2-Methoxyestradiol In Zebrafish Larvae
Autor(es): Quezada M, Alvarez M, Pena O, Henriquez S, D' Alencon C, Lange S, Oliva B, Owen G, Allende M
Año: 2013.157:141-149.
Ref: Quezada M, Alvarez M, Pena O, Henriquez S, d' Alencon C, Lange S, Oliva B, Owen G, Allende M. Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae. Comparative Biochemistry And Physiology C-Toxicology & Pharmacology. 2013;157(2):141-149.

21
Concanavalin-A Induces Granulosa Cell Death And Inhibits Fsh-Mediated Follicular Growth And Ovarian Maturation In Female Rats
Autor(es): Velasquez E, Rios M, Ortiz M, Lizama C, Nunez E, Abramovich D, Orge F, Oliva B, Orellana R, Villalon M, Moreno R, Owen G, Et Al.
Año: 2013.154:1885-1896.
Ref: Velasquez E, Rios M, Ortiz M, Lizama C, Nunez E, Abramovich D, Orge F, Oliva B, Orellana R, Villalon M, Moreno R, Owen G, et al.. Concanavalin-A Induces Granulosa Cell Death and Inhibits FSH-Mediated Follicular Growth and Ovarian Maturation in Female Rats. Endocrinology. 2013;154(5):1885-1896.

22
Different Effects Of Progesterone And Estradiol On Chimeric And Wild Type Aldosterone Synthase In Vitro
Autor(es): Vecchiola A, Lagos C, Fuentes C, Allende F, Campino C, Valdivia C, Tapia A, Ogishima T, Mukai K, Owen G, Solari S, Carvajal C, Fardella C
Año: 2013.11:1-11.
Ref: Vecchiola A, Lagos C, Fuentes C, Allende F, Campino C, Valdivia C, Tapia A, Ogishima T, Mukai K, Owen G, Solari S, Carvajal C, Fardella C. Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro. Reproductive Biology And Endocrinology. 2013;11(76):1-11.

23
Effects Of Statins In Cancer
Autor(es): Cuello M, Kato S, Diaz D, Owen G
Año: 2013.141:227-236.
Ref: Cuello M, Kato S, Diaz D, Owen G. Effects of statins in cancer. Revista Medica De Chile. 2013;141(2):227-236.

24
Breaking Through An Epigenetic Wall Re-Activation Of Oct4 By Krab-Containing Designer Zinc Finger Transcription Factors
Autor(es): Juarez-Moreno K, Erices R, Beltran A, Stolzenburg S, Cuello-Fredes M, Owen G, Qian H, Blancafort P
Año: 2013.8:164-176.
Ref: Juarez-Moreno K, Erices R, Beltran A, Stolzenburg S, Cuello-Fredes M, Owen G, Qian H, Blancafort P. Breaking through an epigenetic wall Re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors. Epigenetics. 2013;8(2):164-176.

25
Involvement Of The Angpts/tie-2 System In Ovarian Hyperstimulation Syndrome (Ohss)
Autor(es): Scotti L, Abramovich D, Pascuali N, De Zuniga I, Oubina A, Kopcow L, Lange S, Owen G, Tesone M, Parborell F
Año: 2013.365:223-230.
Ref: Scotti L, Abramovich D, Pascuali N, de Zuniga I, Oubina A, Kopcow L, Lange S, Owen G, Tesone M, Parborell F. Involvement of the ANGPTs/Tie-2 system in ovarian hyperstimulation syndrome (OHSS). Molecular And Cellular Endocrinology. 2013;365(2):223-230.

26
In Vitro Cell Response To Chemotherapeutic Agents, To Personalize Ovarian Cancer Treatment: Report Of Two Cases
Autor(es): Carolina Ibanez C, Marcelo Garrido S, Medina L, Kato S, Bravo Ml, Gonzalez P, Oliva B, Pizarro J, Bustamante E, Branes J, Cuello M, Owen Gi
Año: 2013.5:669-673.10.4067/S0034-9887201300050001
Ref: Carolina Ibáñez C, Marcelo Garrido S, Medina L, Kato S, Bravo ML, González P, Oliva B, Pizarro J, Bustamante E, Brañes J, Cuello M, Owen GI. In vitro cell response to chemotherapeutic agents, to personalize ovarian cancer treatment: report of two cases. Revista Medica De Chile. 2013;5(141):669-673.

27
Different Effects Of Progesterone And Estradiol On Chimeric And Wild Type Aldosterone Synthase In Vitro
Autor(es): Andrea Vecchiola, Carlos F. Lagos, Cristobal A. Fuentes, Fidel Allende, Carmen Campino, Carolina Valdivia, Tadashi Ogishima, Kuniaki Mukai, Gareth I. Owen, Sandra Solari, Cristian A. Carvajal, Carlos E. Fardella
Año: 2013.11:1-11.10.1186/1477-7827-11-76
Ref: Andrea Vecchiola, Carlos F. Lagos, Cristobal A. Fuentes, Fidel Allende, Carmen Campino, Carolina Valdivia, Tadashi Ogishima, Kuniaki Mukai, Gareth I. Owen, Sandra Solari, Cristian A. Carvajal, Carlos E. Fardella. Different effects of progesterone and estradiol on chimeric and wild type aldosterone synthase in vitro. Reproductive Biology And Endocrinology. 2013;11(76):1-11.

28
Paclitaxel-Phbv Nanoparticles And Their Toxicity To Endometrial And Primary Ovarian Cancer Cells
Autor(es): Vilos C, Morales F, Solar P, Herrera N, Gonzalez-Nilo F, Aguayo D, Mendoza H, Bravo M, Gonzalez P, Kato S, Cuello M, Owen G, Et Al.
Año: 2013.34:4098-4108.
Ref: Vilos C, Morales F, Solar P, Herrera N, Gonzalez-Nilo F, Aguayo D, Mendoza H, Bravo M, Gonzalez P, Kato S, Cuello M, Owen G, et al.. Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials. 2013;34(16):4098-4108.

29
The Identification Of Two Subgroups Of Obese Women With Differing Endometrial Proliferation Levels: Potential Consequences In The Development Of Endometrial Cancer
Autor(es): Villavicencio A , Aguilar G, Acuna J, Gabler F, Soto E , Gaete F, Penaloza P , Celis M , Owen G
Año: 2012.36:1012-1015.
Ref: Villavicencio A , Aguilar G, Acuna J, Gabler F, Soto E , Gaete F, Penaloza P , Celis M , Owen G. The identification of two subgroups of obese women with differing endometrial proliferation levels: potential consequences in the development of endometrial cancer. International Journal Of Obesity. 2012;36(7):1012-1015.

30
Progesterone Promotes Focal Adhesion Formation And Migration In Breast Cancer Cells Through Induction Of Protease-Activated Receptor-1
Autor(es): Diaz J , Aranda E , Henriquez S , Quezada M , Espinoza E , Bravo M, Oliva B , Lange S, Villalon M, Jones M , Brosens J, Kato S, Cuello M, Knutson T, Lange C, Leyton L , Owen G
Año: 2012.214:165-175.
Ref: Diaz J , Aranda E , Henriquez S , Quezada M , Espinoza E , Bravo M, Oliva B , Lange S, Villalon M, Jones M , Brosens J, Kato S, Cuello M, Knutson T, Lange C, Leyton L , Owen G. Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor-1. Journal Of Endocrinology. 2012;214(2):165-175.

31
11 Beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms And Activity In A Chilean Essential Hypertensive And Normotensive Cohort
Autor(es): Campino C, Quinteros H, Owen G, Carvajal C, Morales M, Olivieri O , Guidi G , Faccini G , Pasini F, Baudrand R , Padilla O, Valdivia C , Thichauer J , Lagos C, Kalergis A, Fardella C
Año: 2012.25:597-603.
Ref: Campino C, Quinteros H, Owen G, Carvajal C, Morales M, Olivieri O , Guidi G , Faccini G , Pasini F, Baudrand R , Padilla O, Valdivia C , Thichauer J , Lagos C, Kalergis A, Fardella C. 11 beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms and Activity in a Chilean Essential Hypertensive and Normotensive Cohort. American Journal Of Hypertension. 2012;25(5):597-603.

32
Ppar Alpha And Ppar Gamma Regulate The Nucleoside Transporter Hent1
Autor(es): Montero T, Racordon D , Bravo L , Owen G, Bronfman M, Leisewitz A
Año: 2012.419:405-411.
Ref: Montero T, Racordon D , Bravo L , Owen G, Bronfman M, Leisewitz A. PPAR alpha and PPAR gamma regulate the nucleoside transporter hENT1 . Biochemical And Biophysical Research Communications. 2012;419(2):405-411.

33
The Identification Of Two Subgroups Of Obese Women With Differing Endometrial Proliferation Levels: Potential Consequences In The Development Of Endometrial Cancer
Autor(es): Villavicencio A, Aguilar G, Acua J, Gabler F, Soto E, Gaete F, Pealoza P, Celis M, Owen G
Año: 2012.36:1012-1015.
Ref: Villavicencio A, Aguilar G, Acua J, Gabler F, Soto E, Gaete F, Pealoza P, Celis M, Owen G. The identification of two subgroups of obese women with differing endometrial proliferation levels: Potential consequences in the development of endometrial cancer. International Journal Of Obesity. 2012;36(7):1012-1015.

34
11Beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms And Activity In A Chilean Essential Hypertensive And Normotensive Cohort
Autor(es): Carmen Campino, Hector Quinteros, Gareth I. Owen, Cristian A. Carvajal, Mauricio Morales, Oliviero Olivieri, Giancesare Guidi, Giovanni Faccini, Francesco Pasini, Rene Baudrand, Oslando Padilla, Carolina Valdivia, Juan Tichauer, Carlos F. Lagos, Alexis M. Kalergis, Carlos E. Fardella
Año: 2012.25:597-603.10.1038/ajh.2011.263
Ref: Carmen Campino, Hector Quinteros, Gareth I. Owen, Cristian A. Carvajal, Mauricio Morales, Oliviero Olivieri, Giancesare Guidi, Giovanni Faccini, Francesco Pasini, Rene Baudrand, Oslando Padilla, Carolina Valdivia, Juan Tichauer, Carlos F. Lagos, Alexis M. Kalergis, Carlos E. Fardella. 11beta-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort. American Journal Of Hypertension. 2012;25:597-603.

35
Progesterone Utilizes Distinct Membrane Pools Of Tissue Factor To Increase Coagulation And Invasion And These Effects Are Inhibited By Tfpi
Autor(es): Henriquez S , Calderon C , Quezada M , Oliva B , Bravo M, Aranda E , Kato S , Cuello M, Gutierrez J , Quest A, Owen G
Año: 2011.226:3278-3285.
Ref: Henriquez S , Calderon C , Quezada M , Oliva B , Bravo M, Aranda E , Kato S , Cuello M, Gutierrez J , Quest A, Owen G. Progesterone Utilizes Distinct Membrane Pools of Tissue Factor to Increase Coagulation and Invasion and These Effects are Inhibited by TFPI. Journal Of Cellular Physiology. 2011;226(12):3278-3285.

36
Increased Urinary Glucocorticoid Metabolites Are Associated With Metabolic Syndrome, Hypoadiponectinemia, Insulin Resistance And Beta Cell Dysfunction
Autor(es): Baudrand R , Campino C, Carvajal C, Olivieri O, Guidi G , Faccini G , Sateler J , Cornejo J , San Martin B, Dominguez J, Cerda J , Mosso L, Owen G, Kalergis A, Fardella C
Año: 2011.76:1575-1581.
Ref: Baudrand R , Campino C, Carvajal C, Olivieri O, Guidi G , Faccini G , Sateler J , Cornejo J , San Martin B, Dominguez J, Cerda J , Mosso L, Owen G, Kalergis A, Fardella C. Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and beta cell dysfunction. Steroids. 2011;76(14):1575-1581.

37
Lipophilic But Not Hydrophilic Statins Selectively Induce Cell Death In Gynaecological Cancers Expressing High Levels Of Hmgcoa Reductase
Autor(es): Kato S, Smalley S, Sadarangani A, Chen-Lin K, Oliva B, Branes J, Carvajal J, Gejman R, Owen Gi, Cuello M
Año: 2010.14:1180-1193.
Ref: Kato S, Smalley S, Sadarangani A, Chen-Lin K, Oliva B, Branes J, Carvajal J, Gejman R, Owen GI, Cuello M. Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. Journal Of Cellular And Molecular Medicine. 2010;14(5):1180-1193.

38
11 Beta-Hydroxysteroid Dehydrogenase Type-2 And Type-1 (11 Beta-Hsd2 And 11 Beta-Hsd1) And 5 Beta-Reductase Activities In The Pathogenia Of Essential Hypertension
Autor(es): Campino C, Carvajal Ca, Cornejo J, San Martin B, Olivieri O, Guidi G, Faccini G, Pasini F, Sateler J, Baudrand R, Mosso L, Owen Gi, Kalergis Am, Padilla O, Fardella Ce
Año: 2010.37:106-114.
Ref: Campino C, Carvajal CA, Cornejo J, San Martín B, Olivieri O, Guidi G, Faccini G, Pasini F, Sateler J, Baudrand R, Mosso L, Owen GI, Kalergis AM, Padilla O, Fardella CE. 11 beta-hydroxysteroid dehydrogenase type-2 and type-1 (11 beta-HSD2 and 11 beta-HSD1) and 5 beta-reductase activities in the pathogenia of essential hypertension. Endocrine. 2010;37(1):106-114.

39
2-Methoxyestradiol Inhibits Progesterone-Dependent Tissue Factor Expression And Activity In Breast Cancer Cells
Autor(es): Quezada M, Diaz J, Henriquez S, Bravo M, Aranda E, Oliva B, Villalon M, Kato S, Cuello M, Brosens J, Lange C, Owen G
Año: 2010.1:117-126.
Ref: Quezada M, Diaz J, Henriquez S, Bravo M, Aranda E, Oliva B, Villalon M, Kato S, Cuello M, Brosens J, Lange C, Owen G. 2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells. Hormones And Cancer. 2010;1(3):117-126.

40
Glucose Transporters In Sex Steroid Hormone Related Cancer
Autor(es): Nualart F, Garcia Mdla, Medina Ra, Owen Gi
Año: 2009.7:534-548.
Ref: Nualart F, García MDLA, Medina RA, Owen GI. Glucose Transporters in Sex Steroid Hormone Related Cancer. Current Vascular Pharmacology. 2009;7(4):534-548.

41
A Semi-Quantitative Assay To Screen For Angiogenic Compounds And Compounds With Angiogenic Potential Using The Ea.hy926 Endothelial Cell Line
Autor(es): Aranda E, Owen Gi
Año: 2009.42:377-389.
Ref: Aranda E, Owen GI. A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line. Biological Research. 2009;42(3):377-389.

42
Characterization And Phenotypic Variation With Passage Number Of Cultured Human Endometrial Adenocarcinoma Cells
Autor(es): Kato S, Espinoza N, Lange S, Villalon M, Cuello M, Owen G
Año: 2008.40:95-102.
Ref: Kato S, Espinoza N, Lange S, Villalón M, Cuello M, Owen G. Characterization and phenotypic variation with passage number of cultured human endometrial adenocarcinoma cells. Tissue & Cell. 2008;40(2):95-102.

43
Regulation Of Glut3 And Glucose Uptake By The Camp Signalling Pathway In The Breast Cancer Cell Line Zr-75
Autor(es): Meneses M, Medina R, Kato S, Pinto M, Jaque M, Lizama I, Garcia M, Nualart F, Owen G
Año: 2008.214:110-116.
Ref: Meneses M, Medina R, Kato S, Pinto M, Jaque M, Lizama I, García M, Nualart F, Owen G. Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75. Journal Of Cellular Physiology. 2008;214(1):110-116.

44
Retinoblastoma Protein And The Leukemia-Associated Plzf Transcription Factor Interact To Repress Target Gene Promoters
Autor(es): Petrie K, Guidez F, Zhu J, Howell L, Owen G, Chew Y, Parks S, Waxman S, Licht J, Mittnacht S, Zelent A
Año: 2008.27:5260-5266.
Ref: Petrie K, Guidez F, Zhu J, Howell L, Owen G, Chew Y, Parks S, Waxman S, Licht J, Mittnacht S, Zelent A. Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters. Oncogene. 2008;27(39):5260-5266.

45
Regiones Polimórficas Del Gen 11ß-Hidroxiesteroide Deshidrogenasa Tipo 1 (11ßhsd1) En Hipertensión Arterial Esencial: Posible Rol Etiopatogénico
Autor(es): Morales M, Carvajal C, Ortiz E, Mosso L, Artigas R, Owen G, Fardella C
Año: 2008.136:701-710.
Ref: Morales M, Carvajal C, Ortíz E, Mosso L, Artigas R, Owen G, Fardella C. Regiones polimórficas del gen 11ß-hidroxiesteroide deshidrogenasa tipo 1 (11ßHSD1) en hipertensión arterial esencial: Posible rol etiopatogénico. Revista Medica De Chile. 2008;136(6):701-710.

46
2-Methoxyestradiol Mediates Apoptosis Through Caspase-Dependent And Independent Mechanisms In Ovarian Cancer Cells But Not In Normal Counterparts
Autor(es): Kato S, Sadarangani A, Lange S, Delpiano A, Vargas M, Branes J, Carvajal J, Lipkowitz S, Owen G, Cuello M
Año: 2008.15:878-894.
Ref: Kato S, Sadarangani A, Lange S, Delpiano A, Vargas M, Branes J, Carvajal J, Lipkowitz S, Owen G, Cuello M. 2-Methoxyestradiol Mediates Apoptosis Through Caspase-Dependent and Independent Mechanisms in Ovarian Cancer Cells But Not in Normal Counterparts. Reproductive Sciences. 2008;15(9):878-894.

47
Trail Mediates Apoptosis In Cancerous But Not Normal Primary Cultured Cells Of The Human Reproductive Tract
Autor(es): Sadarangani A, Kato S, Espinoza N, Lange S, Llados C, Espinosa M, Villalon M, Lipkowitz S, Cuello M, Owen G
Año: 2007.12:73-85.
Ref: Sadarangani A, Kato S, Espinoza N, Lange S, Llados C, Espinosa M, Villalón M, Lipkowitz S, Cuello M, Owen G. TRAIL mediates apoptosis in cancerous but not normal primary cultured cells of the human reproductive tract. Apoptosis. 2007;12(1):73-85.

48
The Oestrogen Metabolite 2-Methoxyoestradiol Alone Or In Combination With Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand Mediates Apoptosis In Cancerous But Not Healthy Cells Of The Human Endometrium
Autor(es): Kato S, Sadarangani A, Lange S, Villalon M, Branes J, Brosens J, Owen G, Cuello M
Año: 2007.14:351-368.
Ref: Kato S, Sadarangani A, Lange S, Villalón M, Branes J, Brosens J, Owen G, Cuello M. The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium. Endocrine-Related Cancer. 2007;14(2):351-368.

49
Progesterone Pre-Treatment Potentiates Egf Pathway Signaling In The Breast Cancer Cell Line Zr-75
Autor(es): Carvajal A, Espinoza N, Kato S, Pinto M, Sadarangani A, Monso C, Aranda E, Villalon M, Richer J, Horwitz K, Brosens J, Owen G
Año: 2005.94:171-183.
Ref: Carvajal A, Espinoza N, Kato S, Pinto M, Sadarangani A, Monso C, Aranda E, Villalón M, Richer J, Horwitz K, Brosens J, Owen G. Progesterone Pre-Treatment Potentiates Egf Pathway Signaling in the Breast Cancer Cell Line Zr-75. Breast Cancer Research And Treatment. 2005;94(2):171-183.

50
Progesterone Increases Tissue Factor Gene Expression, Procoagulant Activity, And Invasion In The Breast Cancer Cell Line Zr-75-1
Autor(es): Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Sadarangani A, Villalon M, Bronsens J, White J, Richer J, Horwitz K, Owen G
Año: 2005.90:1181-1188.
Ref: Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Sadarangani A, Villalón M, Bronsens J, White J, Richer J, Horwitz K, Owen G. Progesterone Increases Tissue Factor Gene Expression, Procoagulant Activity, and Invasion in the Breast Cancer Cell Line Zr-75-1. Journal Of Clinical Endocrinology And Metabolism. 2005;90(2):1181-1188.

51
In Vivo And In Vitro Estrogenic And Progestagenic Actions Of Tibolone
Autor(es): Sadarangani A, Salgado A, Kato S, Pinto M, Carvajal A, Monso C, Owen G, Vigil M
Año: 2005.38:1-14.
Ref: Sadarangani A, Salgado A, Kato S, Pinto M, Carvajal A, Monso C, Owen G, Vigil M. In Vivo and in Vitro Estrogenic and Progestagenic Actions of Tibolone. Biological Research. 2005;38(2-3):1-14.

52
Tissue Factor Is Regulated By Epidermal Growth Factor In Normal And Malignant Human Endometrial Epithelial Cells
Autor(es): Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Bravo L, Villalon M, Cuello M, Quest A, Suenaga A, Bronsens J, Owen G
Año: 2005.94:444-453.
Ref: Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Bravo L, Villalón M, Cuello M, Quest A, Suenaga A, Bronsens J, Owen G. Tissue Factor Is Regulated by Epidermal Growth Factor in Normal and Malignant Human Endometrial Epithelial Cells. Thrombosis And Haemostasis. 2005;94(2):444-453.

53
Differential Regulation Of Glucose Transporter Expression By Estrogen And Progesterone In Ishikawa Endometrial Cancer Cells
Autor(es): Medina R, Meneses A, Vera J, Guzman C, Nualart F, Rodriguez F, Garcia M, Kato S, Espinoza N, Monso C, Carvajal A, Pinto M, Owen G
Año: 2004.182:467-478.
Ref: Medina R, Meneses A, Vera J, Guzmán C, Nualart F, Rodríguez F, García M, Kato S, Espinoza N, Monso C, Carvajal A, Pinto M, Owen G. Differential Regulation of Glucose Transporter Expression by Estrogen and Progesterone in Ishikawa Endometrial Cancer Cells. Journal Of Endocrinology. 2004;182(3):467-478.

54
The Action Of Avarian Hormones In Cardiovascular Disease
Autor(es): Medina R, Aranda E, Verdugo C, Kato S, Owen G
Año: 2003.36:325-341.
Ref: Medina R, Aranda E, Verdugo C, Kato S, Owen G. The Action of Avarian Hormones in Cardiovascular Disease. Biological Research. 2003;36:325-341.

55
Estrogen And Progesterone Up-Regulate Glucose Transporter Expression In Zr-75-1 Human Breast Cancer Cells
Autor(es): Medina R, Meneses A, Vera J, Guzman C, Nualart F, Astuya A, Garcia M, Kato S, Carvajal A, Pinto M, Owen G
Año: 2003.144:4527-4535.
Ref: Medina R, Meneses A, Vera J, Guzmán C, Nualart F, Astuya A, García M, Kato S, Carvajal A, Pinto M, Owen G. Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in Zr-75-1 Human Breast Cancer Cells. Endocrinology. 2003;144(10):4527-4535.

56
Glucose Transporters: Expression, Regulation And Cancer
Autor(es): Medina R, Owen G
Año: 2002.35:9-26.
Ref: Medina R, Owen G. Glucose Transporters: Expression, Regulation and Cancer. Biological Research. 2002;35(1):9-26.



Libros y Capitulos de Libros


Nuclear Receptor Genes: Evolution
Autor(es): Saez Pj, Lange S, Perez-Acle T, Owen Gi
Año: 2010:0-0.
Ref: Sáez PJ, Lange S, Pérez-Acle T, Owen GI. Nuclear Receptor Genes: Evolution. In: Encyclopedia of Life Sciences. Chichester: John Wiley & Sons Ltd.; 2010. p. 0-0.

La Ruta De Trail: Un Ejemplo En La Busqueda De Nuevos Tratamientos Para El Cancer De Ovario
Autor(es): Owen G, Cuello M, Kato S, Sadarangani A, Saez C, Gejman R, Lipkowitz S
Año: 2007:435-444.
Ref: Owen G, Cuello M, Kato S, Sadarangani A, Sáez C, Gejman R, Lipkowitz S. La ruta de TRAIL: Un ejemplo en la busqueda de nuevos tratamientos para el cancer de ovario. In: Recalcine Press,editors. Endocrinología II. Chile: Recalcine Press; 2007. p. 435-444.

Nuclear Receptor Genes: Evolution
Autor(es): Owen G.
Año: 2003:1-10.
Ref: Owen G.. Nuclear Receptor Genes: Evolution. In: Nature Encyclopedia of the Human Genome. 2003. p. 1-10.

Sección Patentes

  • Use Of A Fsh Fraction In The Control Of Cell Proliferation