UC
GENÉTICA MOLECULAR Y MICROBIOLOGÍA

KALERGIS PARRA,ALEXIS MIKES

Alexis  Mikes Kalergis Parra Alexis Mikes Kalergis Parra

Laboratorio: 354 2225
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Profesor Titular

Genética Molecular y Microbiología

GENÉTICA MOLECULAR Y MICROBIOLOGÍA,
Facultad de Ciencias Biológicas,
Alameda 340, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.

Antecedentes Académicos

Posdoctorado, The Rockefeller University (2003).
Posdoctorado, Albert Einstein College of Medicine of Yeshiva University (2001).
Doctor, Albert Einstein College of Medicine of Yeshiva University (2000).
Magister, Albert Einstein College of Medicine of Yeshiva University (1997).
Bioquímico, Pontificia Universidad Católica de Chile (1996).

Postdoctorado:

Albert Einstein College of Medicine, NY; The Rockefeller University, NY

Especialización:

Microbiología e Inmunología Celular

Premios y Distinciones

  • Affilated Member for the TWAS, TWAS (2009).
  • Foreing Scientist Award, INSERM (2008).
  • Member of the select young scientist program, Chilean Accademy of Sciences (2006).
  • Young Investigator award, BiosChile (2004).
  • Associated investigator to the Center for Cell Regulation and Pathology, FONDAP-Biomedicine (2003).
  • Juliu Mamur award, Albert Einstein College of Medicine (2000).

Actividades de Docencia

Pregado
  • 2017 BIO389E-1, Inmunología Celular Y Molecular.
  • 2016 BIO389E-1, Inmunología Celular Y Molecular.
  • 2015 BIO389E-1, Inmunología Celular Y Molecular.
Postgrado
  • 2017 BIO4411-1, Inmunología Molecular Avanzada Con Aplicación En Biomedicina.
  • 2016 BIO4411-1, Inmunología Molecular Avanzada Con Aplicación En Biomedicina.
  • 2015 BIO4411-1, Inmunología Molecular Avanzada Con Aplicación En Biomedicina.

Líneas de Investigación

Su área de investigación se enfoca a nivel molecular en la respuesta inmune contra agentes infecciosos y tumores, así como también en re-establecer el equilibrio inmunológico en fenómenos autoinmunes. Recientemente ha conseguido generar una vacuna contra el virus respiratorio sincicicial, la cual se encuentra en proceso de manufactura para su potencial aplicación en humanos. De funcionar, esta vacuna podría solucionar uno de los principales problemas de salud pública que afectan al país. Finalmente, el Dr. Kalergis ha hecho esfuerzos significativos para difundir la ciencia al medio externo, a través de talleres dirigidos a la sociedad, los cuales se han llevado a cabo en todas las regiones del país.

Interacciones moleculares que controlan la sinapsis inmunológica entre la célula dendrítica y el linfocito T. Implicaciones en la defensa contra patógenos y tumores y en la prevención de la autoimunidad. Nuestra línea de investigación se concentra en las interacciones moleculares que promueven la formación de la sinapsis inmunológica entre el linfocito T y la célula dendrítica presentadora de antígenos. Dicha sinapsis es esencial para la respuesta inmune responsable de proteger al hospedero contra los agentes patógenos y el crecimiento de tumores. Específicamente, estos estudios apuntan a dilucidar los mecanismos moleculares por los cuales la célula dendrítica controla la activación del linfocito T. Los nuevos conocimientos generados serán aplicados a la optimización de la inmunidad contra agentes infecciosos bacterianos y virales, así como también contra tumores malignos. Además, nuestro laboratorio intenta identificar los mecanismos moleculares desarrollados por los patógenos y las células tumorales para inhibir la formación de la sinapsis inmunológica, con el objeto de evadir la respuesta inmune. Finalmente, el entendimiento de los mecanismos moleculares responsables de la regulación de la sinapsis inmunológica es clave para interferir con la iniciación y desarrollo de enfermedades autoinmunes, tales como la Esclerosis Múltiple, el Lupus Eritamatoso Sistémico y la Artritis Reumatoide. En el laboratorio estamos desarrollando estrategias tanto de inmunoterapia como farmacológicas modular la sinapsis inmunológica a fin de evitar el desarrollo de autoinmunidad.


Titulo: Elucidating The Mechanisms Of Pathogenicity Used By The Human Respiratory Syncytial Virus To Prevent T Cell Activation And Cause Central Nervous System Inflammation.
Año: 2015
Concurso e institución: Regular, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes, Riedel Claudia, Bueno Ramirez Susan Marcela, Gonzalez Munoz Pablo Alberto
Fecha inicio: 01-03-2015
Fecha termino: 01-03-2019
Duración: 48 meses

Titulo: Ho-1 Expression Protects From Kidney Damage Induced By Innate Immunity During Lupus Nephritis
Año: 2015
Concurso e institución: Regular, CONICYT
Investigador principal: Llanos Munoz Carolina
Otros investigadores: Llanos Munoz Carolina, Jacobelli Sergio, Mendez Olivieri Gonzalo Patricio, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2015
Fecha termino: 01-03-2018
Duración: 36 meses

Titulo: Rol De Glicoproteinas De Superficie Del Virus Herpes Simplex-2 Sobre La Función De Celulas Dendriticas
Año: 2014
Concurso e institución: Regular, CONICYT
Investigador principal: Gonzalez Munoz Pablo Alberto
Otros investigadores: Gonzalez Munoz Pablo Alberto, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2014
Fecha termino: 01-03-2018
Duración: 48 meses

Titulo: Role Of Interleukin 10 (Il-10) In The Ability Of Bacterial Pathogens To Cause Systemic Infections In The Host
Año: 2014
Concurso e institución: Regular, CONICYT
Investigador principal: Bueno Ramirez Susan Marcela
Otros investigadores: Bueno Ramirez Susan Marcela, Kalergis Parra Alexis Mikes, Riedel Soria Claudia Andrea
Fecha inicio: 01-03-2014
Fecha termino: 01-03-2017
Duración: 36 meses

Titulo: Evaluación Neurocognitiva Posterior A Infección Grave Por Virus Respiratorio Sincicial En Lactantes.
Año: 2013
Concurso e institución: Interdisciplina, UC
Investigador principal: Borzutzky Schachter Arturo Jose
Otros investigadores: Borzutzky Schachter Arturo Jose, Kalergis Parra Alexis Mikes, Pena Garay Marcela De Lourdes
Fecha inicio: 01-11-2013
Fecha termino: 01-11-2015
Duración: 24 meses

Titulo: Salt Intake In Essential Hypertension: Studies Of New Biochemical And Genetic Mechanisms To Identify Its Etiology
Año: 2013
Concurso e institución: Regular, CONICYT
Investigador principal: Fardella Bello Carlos Enrique
Otros investigadores: Fardella Bello Carlos Enrique, Martinez Aguayo Alejandro Gregorio, Campino Johnson Maria Del Carmen, Carrasco Mardones Carmen Maria Antonieta, Carvajal Maldonado Cristian Andres, Garcia Bruce Hernan Gabriel, Aglony Imbarack Marlene Elizabeth, Kalergis Parra Alexis Mikes, Baudrand Biggs Rene Felipe
Fecha inicio: 01-03-2013
Fecha termino: 01-03-2016
Duración: 36 meses

Titulo: Assessment Of Rationally Designed Small Molecule Inhibitors Targeting The Human Respiratory Syncytial Virus Matrix Protein
Año: 2013
Concurso e institución: Regular, CONICYT
Investigador principal: Schueller Andreas Peter
Otros investigadores: Schueller Andreas Peter, Melo Ledermann Francisco Javier, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2013
Fecha termino: 01-03-2016
Duración: 36 meses

Titulo: Role Of Heme Oxygenase-1 In Acute And Chronc Intestinal Inflamation: Infectious And Immune Models
Año: 2013
Concurso e institución: Regular, CONICYT
Investigador principal: Alvarez Lobos Manuel Marcelo
Otros investigadores: Alvarez Lobos Manuel Marcelo, Bueno Ramirez Susan Marcela, Ibanez Lazo Patricio Fernando, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2013
Fecha termino: 01-03-2017
Duración: 48 meses

Titulo: Estudio De La Respuesta Inmune Moduladas Por Celulas Epitetiales Humanas Hacia El Virus Respiratorio Sindical Y El Metapneumovirus Humano
Año: 2011
Concurso e institución: Postdoctorado, CONICYT
Investigador principal: Lay Remolcoi Margarita
Otros investigadores: Lay Remolcoi Margarita, Kalergis Parra Alexis Mikes
Fecha inicio: 01-10-2011
Fecha termino: 01-10-2014
Duración: 36 meses

Titulo: Instituto Milenio En Inmunologia E Inmunoterapia
Año: 2011
Concurso e institución: Instituto Ciencias Naturales Y Exactas, Ministerio de Economía
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes, Gonzalez Munoz Pablo Alberto
Fecha inicio: 01-06-2011
Fecha termino: 01-06-2021
Duración: 120 meses

Titulo: Identification Of The Mechanisms Used By The Respiratory Syncytial Virus (Rsv) To Interfere With The Function Of Dendritic Cells And Impair T Cell Immunity In The Host
Año: 2011
Concurso e institución: Regular, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2011
Fecha termino: 01-03-2015
Duración: 48 meses

Titulo: Maternal Hypothyroxinemia Increases The Susceptibility To Develop Inflammatory Demyelination In The Offspring
Año: 2010
Concurso e institución: Regular, CONICYT
Investigador principal: Riedel Claudia
Otros investigadores: Riedel Claudia, Kalergis Parra Alexis Mikes, Carreno Leandro
Fecha inicio: 01-03-2010
Fecha termino: 01-03-2013
Duración: 36 meses

Titulo: Modulation Of T Cell Activation By Human Metapneuromovirus-Infected Dentritic Cells
Año: 2009
Concurso e institución: Postdoctorado, CONICYT
Investigador principal: Gonzalez Muoz Pablo
Otros investigadores: Gonzalez Munoz Pablo, Kalergis Parra Alexis Mikes
Fecha inicio: 01-10-2009
Fecha termino: 01-10-2011
Duración: 24 meses

Titulo: Estudio De La Expresión Y Regulación Diferencial De Los Receptores Fcy Activadores De Ihibidores En La Célula Dentritica En Lupus Erimatoso Sistémico: Impacto En La Activación De Linfocitos T Autoreactivos.
Año: 2008
Concurso e institución: Regular, CONICYT
Investigador principal: Iacobelli Gabrielli Sergio Hernan
Otros investigadores: Iacobelli Gabrielli Sergio Hernan, Gutierrez Torres Miguel Alejandro, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2008
Fecha termino: 01-03-2011
Duración: 36 meses

Titulo: Desarrollo De Una Nueva Droga Antitumoral Para El Tratamiento De Cánceres Del Tracto Reproductivo Femenino
Año: 2008
Concurso e institución: Investigación Y Desarrollo, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2008
Fecha termino: 01-01-2011
Duración: 36 meses

Titulo: Caracterizacion Celular Y Molecular De Un Nuevo Mecanismo De Patogenicidad De Salmonella: Inhibicion De La Capacidad De La Celula Dendritica De Activar A Linfocitos T Para Evadir La Respuesta Inmune Adquirida Del Hospedero
Año: 2007
Concurso e institución: Regular, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2007
Fecha termino: 01-03-2010
Duración: 36 meses

Titulo: Caracterizacion Celular Y Molecular De Un Nuevo Mecanismo De Patogenicidad De Salmonella: Inhibicion De La Capacidad De La Celula Dendritica De Activar A Linfocitos T Para Evadir La Respuesta Inmune Adquirida Del Hospedero.
Año: 2007
Concurso e institución: Incentivo A La Cooperación Internacional, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2007
Fecha termino: 01-03-2008
Duración: 12 meses

Titulo: Novel Therapeutic And Prophylactic Strategies To Control Mucosal Infections By South American Bacterial Strains - Savinmucopath
Año: 2007
Concurso e institución: , Comunidad Europea
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2007
Fecha termino: 01-01-2010
Duración: 36 meses

Titulo: Novel Therapeutic And Prophylactic Strategies To Control Mucosal Infections By South American Bacterial Strains - Savinmucopath
Año: 2007
Concurso e institución: , Comunidad Europea
Investigador principal: Cabrera Oyarzun Alejandro Leopoldo
Otros investigadores: Cabrera Oyarzun Alejandro Leopoldo, Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2007
Fecha termino: 01-01-2010
Duración: 36 meses

Titulo: Consorcio Tecnológico Empresarial En Biomedicina Clinico Molecular Aplicada
Año: 2007
Concurso e institución: , PBCT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2007
Fecha termino: 01-01-2012
Duración: 60 meses

Titulo: Rol De La Hemo-Oxigenasa 1 Y Monóxido De Carbono En La Presentación De Antígenos Por Las Células Dendríticas
Año: 2007
Concurso e institución: Ecos (Francia), CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2007
Fecha termino: 01-01-2010
Duración: 36 meses

Titulo: Evaluación Del Estado Funcional De Las Células Dendríticas En El Lupus Eritematoso Sistémico
Año: 2005
Concurso e institución: Regular, CONICYT
Investigador principal: Iacobelli Gabrielli Sergio Hernan
Otros investigadores: Iacobelli Gabrielli Sergio Hernan, Gutierrez Torres Miguel Alejandro, Kalergis Parra Alexis Mikes
Fecha inicio: 01-03-2005
Fecha termino: 01-03-2008
Duración: 36 meses

Titulo: Núcleo Milenio En Inmunología E Inmunoterapia
Año: 2005
Concurso e institución: Núcleo Milenio, MIDEPLAN
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2005
Fecha termino: 01-01-2011
Duración: 72 meses

Titulo: Generación De Una Vacuna Recombinante Contra El Virus Respiratorio Sincicial
Año: 2005
Concurso e institución: Investigación Y Desarrollo, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2005
Fecha termino: 01-01-2008
Duración: 36 meses

Titulo: Inducing Cellular Immunity Against ''piscirickettsia Salmonis'' In Salmón By Immune Complex Vaccination
Año: 2004
Concurso e institución: , Otro
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2004
Fecha termino: 01-01-2006
Duración: 24 meses

Titulo: Estudio De Las Interacciones Moleculares Necesarias Para La Sinapsis Inmunológica Entre La Célula Dendrítica Y El Linfocito T. Implicaciones En La Inmunidad Anti-Bacteriana
Año: 2003
Concurso e institución: Regular, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes, Mora Longa Guido Carlos
Fecha inicio: 01-03-2003
Fecha termino: 01-03-2007
Duración: 48 meses

Titulo: Estudio De Las Interacciones Moleculares Necesarias Para La Sinapsis Inmunológica Entre La Célula Dendrítica Y El Linfocito T. Implicaciones En La Inmunidad Anti-Bacteriana
Año: 2003
Concurso e institución: Inicio, UC
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2003
Fecha termino: 01-01-2005
Duración: 24 meses

Titulo: Generacion De Una Vacuna Contra El Virus Respiratorio Sincicial
Año: 2002
Concurso e institución: Investigación Y Desarrollo, CONICYT
Investigador principal: Kalergis Parra Alexis Mikes
Otros investigadores: Kalergis Parra Alexis Mikes
Fecha inicio: 01-01-2002
Fecha termino: 01-01-2003
Duración: 12 meses


Publicaciones ISI

1
Hormonal Modulation Of Dendritic Cells Differentiation, Maturation And Function: Implications For The Initiation And Progress Of Systemic Autoimmunity
Autor(es): Mackern J, Kalergis A, Jara E, Riedel C
Año: 2017.65:123-136.
Ref: Mackern J, Kalergis A, Jara E, Riedel C. Hormonal Modulation of Dendritic Cells Differentiation, Maturation and Function: Implications for the Initiation and Progress of Systemic Autoimmunity. Archivum Immunologiae Et Therapiae Experimentalis. 2017;65(2):123-136.

2
Endothelial-To-Mesenchymal Transition: Cytokine-Mediated Pathways That Determine Endothelial Fibrosis Under Inflammatory Conditions
Autor(es): Kalergis A, Perez L, Munoz N, Riedel C, Echeverria C, Cabello C, Simon F
Año: 2017.33:41-54.
Ref: Kalergis A, Perez L, Munoz N, Riedel C, Echeverria C, Cabello C, Simon F. Endothelial-to-mesenchymal transition: Cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions. Cytokine & Growth Factor Reviews. 2017;33(-):41-54.

3
Immunological Features Of Respiratory Syncytial Virus-Caused Pneumonia-Implications For Vaccine Design
Autor(es): Rey E, Kalergis A
Año: 2017.18:---.
Ref: Rey E, Kalergis A. Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design. International Journal Of Molecular Sciences. 2017;18(3):---.

4
A Potential Role Of Salmonella Infection In The Onset Of Inflammatory Bowel Diseases
Autor(es): Schultz B, Paduro C, Salazar G, Salazar F, Sebastian V, Riedel C, Kalergis A, Alvarez M, Bueno S
Año: 2017.8:---.
Ref: Schultz B, Paduro C, Salazar G, Salazar F, Sebastian V, Riedel C, Kalergis A, Alvarez M, Bueno S. A Potential Role of Salmonella Infection in the Onset of Inflammatory Bowel Diseases. Frontiers In Immunology. 2017;8(-):---.

5
Innate Immunity And Inflammation In Nafld/nash
Autor(es): Arrese M, Cabrera D, Kalergis A, Feldstein A
Año: 2016.61:1294-1303.
Ref: Arrese M, Cabrera D, Kalergis A, Feldstein A. Innate Immunity and Inflammation in NAFLD/NASH. Digestive Diseases And Sciences. 2016;61(5):1294-1303.

6
Opposing Roles Of Il-10 In Acute Bacterial Infection
Autor(es): Schultz B, Nieto P, Salazar G, Suazo I, Gonzalez P, Riedel C, Alvarez M, Kalergis A, Bueno S, Penaloza H
Año: 2016.32:17-30.
Ref: Schultz B, Nieto P, Salazar G, Suazo I, Gonzalez P, Riedel C, Alvarez M, Kalergis A, Bueno S, Penaloza H. Opposing roles of IL-10 in acute bacterial infection. Cytokine & Growth Factor Reviews. 2016;32(-):17-30.

7
Cortisol/cortisone Ratio And Matrix Metalloproteinase-9 Activity Are Associated With Pediatric Primary Hypertension
Autor(es): Martinez A, Campino C , Baudrand R, Carvajal C, Garcia H, Aglony M, Bancalari R, Garcia L, Loureiro C, Vecchiola A, Tapia A, Valdivia C, Sanhueza S, Fuentes C, Lagos C, Solari S, Allende F, Kalergis A, Fardella C
Año: 2016.34:1808-1814.
Ref: Martinez A, Campino C , Baudrand R, Carvajal C, Garcia H, Aglony M, Bancalari R, Garcia L, Loureiro C, Vecchiola A, Tapia A, Valdivia C, Sanhueza S, Fuentes C, Lagos C, Solari S, Allende F, Kalergis A, Fardella C. Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. Journal Of Hypertension. 2016;34(9):1808-1814.

8
Neutrophil/lymphocyte Ratio In Complete Blood Count As A Mortality Predictor In Breast Cancer
Autor(es): Mimica X, Acevedo F, Oddo D, Ibanez C, Medina L, Kalergis A, Camus M, Sanchez C
Año: 2016.144:691-696.
Ref: Mimica X, Acevedo F, Oddo D, Ibanez C, Medina L, Kalergis A, Camus M, Sanchez C. Neutrophil/lymphocyte ratio in complete blood count as a mortality predictor in breast cancer. Revista Medica De Chile. 2016;144(6):691-696.

9
Citosine-Adenine-Repeat Microsatellite Of 11β-Hydroxysteroid Dehydrogenase 2 Gene In Hypertensive Children
Autor(es): Carolina Valdivia, Cristian A. Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F. Lagos, Alejandra Tapia-Castillo, Cristobal A. Fuentes, Marlene Aglony, Sandra Solari, Alexis M. Kalergis, Hernan Garcia, Gareth I. Owen, Carlos E. Fardella
Año: 2016.29:25-32.10.1093/ajh/hpv052
Ref: Carolina Valdivia, Cristian A. Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F. Lagos, Alejandra Tapia-Castillo, Cristobal A. Fuentes, Marlene Aglony, Sandra Solari, Alexis M. Kalergis, Hernan García, Gareth I. Owen, Carlos E. Fardella. Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children. American Journal Of Hypertension. 2016;29(1):25-32.

10
Role Of The Renin-Angiotensin-Aldosterone System Beyond Blood Pressure Regulation: Molecular And Cellular Mechanisms Involved In End-Organ Damage During Arterial Hypertension
Autor(es): Munoz N, Fuentes C, Castillo A, Gonzalez L, Vecchiola A, Fardella C, Kalergis A
Año: 2016.17:1-17.
Ref: Munoz N, Fuentes C, Castillo A, Gonzalez L, Vecchiola A, Fardella C, Kalergis A. Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension. International Journal Of Molecular Sciences. 2016;17(7):1-17.

11
Citosine-Adenine-Repeat Micrisatellite Of 11B-Hydroxysteroid Dehydrogensase 2 Gene In Hypertensive Children
Autor(es): Cristian Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Sandra Solari, Alexis Kalergis, Hernan Garcia, Gareth Owen, Carlos Fardella
Año: 2016.29:25-32.10.1093/ajh/hpv052
Ref: Cristian Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Sandra Solari, Alexis Kalergis, Hernan Garcia, Gareth Owen, Carlos Fardella. Citosine-Adenine-Repeat Micrisatellite of 11b-hydroxysteroid dehydrogensase 2 gene in hypertensive children. American Journal Of Hypertension. 2016;29(1):25-32.

12
Gestational Hypothyroidism Improves The Ability Of The Female Offspring To Clear Streptococcus Pneumoniae Infection And To Recover From Pneumococcal Pneumonia
Autor(es): Nieto P, Penaloza H, Salazar F, Castellanos R, Opazo M, Venegas L, Padilla O, Kalergis A, Riedel C, Bueno S
Año: 2016.157:2217-2228.
Ref: Nieto P, Penaloza H, Salazar F, Castellanos R, Opazo M, Venegas L, Padilla O, Kalergis A, Riedel C, Bueno S. Gestational Hypothyroidism Improves the Ability of the Female Offspring to Clear Streptococcus pneumoniae Infection and to Recover From Pneumococcal Pneumonia. Endocrinology. 2016;157(6):2217-2228.

13
Potenciales Consecuencias Neurocognitivas De Infección Por Virus Respiratorio Sincicial Humano
Autor(es): Juan Carlos Flores, Karen Bohmwald, Janyra Espinoza, Maria Cristina Jara, Marcela Pena, Rodriogo Hoyos-Bachiloglu, Alexis Kalergis, Arturo Borzutzky
Año: 2016.33:537-542.
Ref: Juan Carlos Flores, Karen Bohmwald, Janyra Espinoza, María Cristina Jara, Marcela Peña, Rodriogo Hoyos-Bachiloglu, Alexis Kalergis, Arturo Borzutzky. Potenciales consecuencias neurocognitivas de infección por virus respiratorio sincicial humano. Revista Chilena de Infectologia. 2016;33(5):537-542.

14
New Insights About Excisable Pathogenicity Islands In Salmonella And Their Contribution To Virulence
Autor(es): Nieto P, Pardo C, Salazar F, Tobar H, Coronado I, Riedel C, Kalergis A, Bueno S
Año: 2016.18:302-309.
Ref: Nieto P, Pardo C, Salazar F, Tobar H, Coronado I, Riedel C, Kalergis A, Bueno S. New insights about excisable pathogenicity islands in Salmonella and their contribution to virulence. Microbes And Infection. 2016;18(5):302-309.

15
Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution And Neuronal Plasticity Through Neuron-Astrocyte Interplay
Autor(es): Cisternas P, Louveau A, Bueno Sm, Kalergis Am, Boudin H, Riedel Ca
Año: 2016.53:7158-7169.
Ref: Cisternas P, Louveau A, Bueno SM, Kalergis AM, Boudin H, Riedel CA. Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay. Molecular Neurobiology. 2016;53(10):7158-7169.

16
Human Respiratory Syncytial Virus: Infection And Pathology
Autor(es): Bohmwald K, Espinoza J, Rey-Jurado E, Gomez R, Gonzalez P, Bueno S, Riedel C, Kalergis A
Año: 2016.37:522-537.
Ref: Bohmwald K, Espinoza J, Rey-Jurado E, Gomez R, Gonzalez P, Bueno S, Riedel C, Kalergis A. Human Respiratory Syncytial Virus: Infection and Pathology. Seminars In Respiratory And Critical Care Medicine. 2016;37(4):522-537.

17
Opposing Roles Of Il-10 In Acute Bacterial Infection. Peñaloza Hf, Schultz Bm, Nieto Pa, Salazar Ga, Suazo I, Gonzalez Pa, Riedel Ca, Alvarez-Lobos Mm, Kalergis Am, Bueno Sm*. Cytokine Growth Factor Rev. 2016 Doi:
Autor(es): Penaloza Hf, Schultz Bm, Nieto P, Salazar Ga, Suazo I, Gonzalez Pa, Riedel C, Alvarez-Lobos M, Kalergis Am, Bueno Am
Año: 2016.32:17-30.10.1016/j.cytogfr.2016.07.003.
Ref: Peñaloza HF, Schultz BM, Nieto P, Salazar GA, Suazo I, Gonzalez PA, Riedel C, Alvarez-Lobos M, Kalergis AM, Bueno AM. Opposing roles of IL-10 in acute bacterial infection. Peñaloza HF, Schultz BM, Nieto PA, Salazar GA, Suazo I, Gonzalez PA, Riedel CA, Alvarez-Lobos MM, Kalergis AM, Bueno SM*. Cytokine Growth Factor Rev. 2016 doi: . Cytokine & Growth Factor Reviews. 2016;32(Dec):17-30.

18
Potential Neurocognitive Consequences Of Infection By Human Respiratory Syncytial Virus
Autor(es): Bohmwald K, Flores J, Espinoza J, Jara C, Pena M, Hoyos R, Iturriaga C, Kalergis A, Borzutzky A
Año: 2016.33:537-542.
Ref: Bohmwald K, Flores J, Espinoza J, Jara C, Pena M, Hoyos R, Iturriaga C, Kalergis A, Borzutzky A. Potential neurocognitive consequences of infection by human respiratory syncytial virus. Revista Chilena De Infectologia. 2016;33(5):537-542.

19
Modulation Of Host Immunity By The Human Metapneumovirus
Autor(es): Cespedes P, Palavecino C, Kalergis A, Bueno S
Año: 2016.29:795-818.
Ref: Cespedes P, Palavecino C, Kalergis A, Bueno S. Modulation of Host Immunity by the Human Metapneumovirus. Clinical Microbiology Reviews. 2016;29(4):795-818.

20
New Insights On The Viral And Host Factors Contributing To The Airway Pathogenesis Caused By The Respiratory Syncytial Virus
Autor(es): Lay M, Bueno S, Galvez N, Riedel C, Kalergis A
Año: 2016.42:800-812.
Ref: Lay M, Bueno S, Galvez N, Riedel C, Kalergis A. New insights on the viral and host factors contributing to the airway pathogenesis caused by the respiratory syncytial virus. Critical Reviews In Microbiology. 2016;42(5):800-812.

21
Modulation Of Antigen Processing By Haem-Oxygenase 1. Implications On Inflammation And Tolerance
Autor(es): Riquelme S, Carreno L, Espinoza J, Mackern J, Alvarez M, Riedel C, Bueno S, Kalergis A
Año: 2016.149:1-12.
Ref: Riquelme S, Carreno L, Espinoza J, Mackern J, Alvarez M, Riedel C, Bueno S, Kalergis A. Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance. Immunology. 2016;149(1):1-12.

22
Citosine-Adenine-Repeat Microsatellite Of 11Â-Hydroxysteroid Dehydrogenase 2 Gene In Hypertensive Children
Autor(es): Carolina Valdivia, Cristian A Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F Lagos, Alejandra Tapia-Castillo, Cristobal A Fuentes, Marlene Aglony, Sandra Solari, Alexis M Kalergis, Hernan Garcia, Gareth I Owen, Carlos E Fardella
Año: 2016.1:25-32.10.1093/ajh/hpv052
Ref: Carolina Valdivia, Cristian A Carvajal, Carmen Campino, Fidel Allende, Alejandro Martinez-Aguayo, Rene Baudrand, Andrea Vecchiola, Carlos F Lagos, Alejandra Tapia-Castillo, Cristobal A Fuentes, Marlene Aglony, Sandra Solari, Alexis M Kalergis, Hernan Garcia, Gareth I Owen, Carlos E Fardella. Citosine-Adenine-Repeat Microsatellite of 11â-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children. American Journal Of Hypertension. 2016;1(29):25-32.

23
Cortisol/cortisone Ratio And Matrix Metalloproteinase-9 Activity Are Associated With Pediatric Primary Hypertension
Autor(es): Alejandro Martinez-Aguayo, Carmen Campino, Rene Baudrand, Cristian A. Carvajal, Hernan Garcia, Marlene Aglony, Rodrigo Bancalari, Lorena Garcia, Carolina Loureiro, Andrea Vecchiola, Alejandra Tapia-Castillo, Carolina Valdivia, Sebastian Sanhueza, Cristobal A. Fuentes, Carlos F. Lagos, Sandra Solari, Fidel Allende, Alexis M. Kalergis, Carlos E. Fardella
Año: 2016.34:1808-1814.10.1097/HJH.0000000000001017
Ref: Alejandro Martinez-Aguayo, Carmen Campino, Rene Baudrand, Cristian A. Carvajal, Hernán García, Marlene Aglony, Rodrigo Bancalari, Lorena García, Carolina Loureiro, Andrea Vecchiola, Alejandra Tapia-Castillo, Carolina Valdivia, Sebastian Sanhueza, Cristobal A. Fuentes, Carlos F. Lagos, Sandra Solari, Fidel Allende, Alexis M. Kalergis, Carlos E. Fardella. Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension. Journal Of Hypertension. 2016;34:1808-1814.

24
Citosine-Adenine-Repeat Microsatellite Of 11 Beta-Hydroxysteroid Dehydrogenase 2 Gene In Hypertensive Children
Autor(es): Valdivia C, Carvajal C, Campino C, Allende F, Martinez A, Baudrand R, Vecchiola A, Lagos C, Tapia A, Fuentes C, Aglony M, Solari S, Kalergis A, Garcia H, Owen G, Fardella C
Año: 2016.29:25-32.
Ref: Valdivia C, Carvajal C, Campino C, Allende F, Martinez A, Baudrand R, Vecchiola A, Lagos C, Tapia A, Fuentes C, Aglony M, Solari S, Kalergis A, Garcia H, Owen G, Fardella C. Citosine-Adenine-Repeat Microsatellite of 11 beta-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children. American Journal Of Hypertension. 2016;29(1):25-32.

25
Contribution Of Fc Gamma Receptors To Human Respiratory Syncytial Virus Pathogenesis And The Impairment Of T-Cell Activation By Dendritic Cells
Autor(es): Gomez R, Ramirez B, Cespedes P, Cautivo K, Riquelme S, Prado C, Gonzalez P, Kalergis A
Año: 2016.147:55-72.
Ref: Gomez R, Ramirez B, Cespedes P, Cautivo K, Riquelme S, Prado C, Gonzalez P, Kalergis A. Contribution of Fc gamma receptors to human respiratory syncytial virus pathogenesis and the impairment of T-cell activation by dendritic cells. Immunology. 2016;147(1):55-72.

26
Interleukin-10 Plays A Key Role In The Modulation Of Neutrophils Recruitment And Lung Inflammation During Infection By Streptococcus Pneumoniae
Autor(es): Penaloza H, Nieto P, Munoz N, Salazar F, Torres J , Parga M, Alvarez M, Riedel C, Kalergis A, Bueno S
Año: 2015.146:100-112.
Ref: Penaloza H, Nieto P, Munoz N, Salazar F, Torres J , Parga M, Alvarez M, Riedel C, Kalergis A, Bueno S. Interleukin-10 plays a key role in the modulation of neutrophils recruitment and lung inflammation during infection by Streptococcus pneumoniae. Immunology. 2015;146(1):100-112.

27
Purification And Characterization Of Saxitoxin From Mytilus Chilensis Of Southern Chile
Autor(es): Rubio D, Roa L, Soto D, Velasquez F, Gregorcic N, Soto J, Martinez C , Kalergis A, Vasquez A
Año: 2015.108:147-153.
Ref: Rubio D, Roa L, Soto D, Velasquez F, Gregorcic N, Soto J, Martinez C , Kalergis A, Vasquez A. Purification and characterization of saxitoxin from Mytilus chilensis of southern Chile. Toxicon. 2015;108:147-153.

28
Contribution Of Autophagy To Antiviral Immunity
Autor(es): Rey E, Riedel C, Gonzalez P, Bueno S, Kalergis A
Año: 2015.589:3461-3470.
Ref: Rey E, Riedel C, Gonzalez P, Bueno S, Kalergis A. Contribution of autophagy to antiviral immunity. Febs Letters. 2015;589(22):3461-3470.

29
The Expression Of Rac1 And Mineralocorticoid Pathway-Dependent Genes Are Associated With Different Responses To Salt Intake.
Autor(es): Tapia-Castillo A, Carvajal Ca, Campino C, Hill C, Allende F, Vecchiola A, Carrasco C, Valdivia C, Lagos C, Martinez-Aguayo A, Garcia H, Aglony M, Baudrand Rf, Kalergis Am, Michea Lf, Riedel Ca, Fardella Ce
Año: 2015.6:722-728.10.1093/ajh/hpu224
Ref: Tapia-Castillo A, Carvajal CA, Campino C, Hill C, Allende F, Vecchiola A, Carrasco C, Valdivia C, Lagos C, Martinez-Aguayo A, Garcia H, Aglony M, Baudrand RF, Kalergis AM, Michea LF, Riedel CA, Fardella CE. The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake.. American Journal Of Hypertension. 2015;6(28):722-728.

30
Carbon Monoxide Inhibits T Cell Activation In Target Organs During Systemic Lupus Erythematosus
Autor(es): Mackern J, Obreque J, Mendez G, Llanos C, Kalergis A
Año: 2015.182:1-13.
Ref: Mackern J, Obreque J, Mendez G, Llanos C, Kalergis A. Carbon monoxide inhibits T cell activation in target organs during systemic lupus erythematosus. Clinical And Experimental Immunology. 2015;182(1):1-13.

31
Immune Evasion By Herpes Simplex Viruses
Autor(es): Retamal-Diaz, Ar, Suazo, Pa, Garrido, I, Kalergis, Am, Gonzalez, Pa
Año: 2015.1:58-70.
Ref: Retamal-Diaz, AR, Suazo, PA, Garrido, I, Kalergis, AM, Gonzalez, PA. Immune evasion by herpes simplex viruses. Revista Chilena De Infectología. 2015;1(32):58-70.

32
New Clinical Advances In Immunotherapy For The Treatment Of Solid Tumours
Autor(es): Zavala V, Kalergis A
Año: 2015.145:182-201.
Ref: Zavala V, Kalergis A. New clinical advances in immunotherapy for the treatment of solid tumours. Immunology. 2015;145(2):182-201.

33
Inflammatory Damage On Respiratory And Nervous Systems Due To Hrsv Infection
Autor(es): Bohmwald K, Espinoza J, Becerra D, Rivera K, Lay M, Bueno S, Riedel C, Kalergis A
Año: 2015.36:14-21.
Ref: Bohmwald K, Espinoza J, Becerra D, Rivera K, Lay M, Bueno S, Riedel C, Kalergis A. Inflammatory damage on respiratory and nervous systems due to hRSV infection. Current Opinion In Immunology. 2015;36:14-21.

34
Modulation Of Immunity And Inflammation By The Mineralocorticoid Receptor And Aldosterone
Autor(es): Munoz N, Vecchiola A, Gonzalez L, Simon F, Riedel C, Fardella C, Kalergis A
Año: 2015.:1-15.
Ref: Munoz N, Vecchiola A, Gonzalez L, Simon F, Riedel C, Fardella C, Kalergis A. Modulation of Immunity and Inflammation by the Mineralocorticoid Receptor and Aldosterone. Biomed Research International. 2015;(652738):1-15.

35
Understanding Lung Immunopathology Caused By The Human Metapneumovirus: Implications For Rational Vaccine Design
Autor(es): Palavecino C, Cespedes P, Lay M, Riedel C, Kalergis A, Bueno S
Año: 2015.35:185-202.
Ref: Palavecino C, Cespedes P, Lay M, Riedel C, Kalergis A, Bueno S. Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design. Critical Reviews In Immunology. 2015;35(3):185-202.

36
Evasion Of Early Antiviral Responses By Herpes Simplex Viruses
Autor(es): Suazo Pa, Ibanez Fj, Retamal-Diaz Ar, Paz-Fiblas Mv, Bueno Sm, Kalergis Am, Gonzalez Pa
Año: 2015.2015:1-16.10.1155/2015/593757
Ref: Suazo PA, Ibañez FJ, Retamal-Díaz AR, Paz-Fiblas MV, Bueno SM, Kalergis AM, Gonzalez PA. Evasion of Early Antiviral Responses by Herpes Simplex Viruses. Mediators Of Inflammation. 2015;2015(1):1-16.

37
Carbon Monoxide Down-Modulates Toll-Like Receptor 4/md2 Expression On Innate Immune Cells And Reduces Endotoxic Shock Susceptibility
Autor(es): Riquelme Sa, Bueno Sm, Kalergis Am
Año: 2015.2:321-332.10.1111/imm.12375
Ref: Riquelme SA, Bueno SM, Kalergis AM. Carbon monoxide down-modulates Toll-like receptor 4/MD2 expression on innate immune cells and reduces endotoxic shock susceptibility. Immunology. 2015;2(144):321-332.

38
Role Of Dendritic Cells In The Initiation, Progress And Modulation Of Systemic Autoimmune Diseases
Autor(es): Mackern-Oberti J, Llanos C, Vega F, Salazar-Onfray F, Riedel C, Bueno S, Kalergis A
Año: 2015.14:127-139.
Ref: Mackern-Oberti J, Llanos C, Vega F, Salazar-Onfray F, Riedel C, Bueno S, Kalergis A. Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases. Autoimmunity Reviews. 2015;14(2):127-139.

39
Novel Therapies And Vaccines Against The Human Respiratory Syncytial Virus
Autor(es): Rivera C, Gomez R, Diaz R, Cespedes P, Espinoza J, Gonzalez P, Riedel C, Bueno S, Kalergis A
Año: 2015.24:1613-1630.
Ref: Rivera C, Gomez R, Diaz R, Cespedes P, Espinoza J, Gonzalez P, Riedel C, Bueno S, Kalergis A. Novel therapies and vaccines against the human respiratory syncytial virus. Expert Opinion On Investigational Drugs. 2015;24(12):1613-1630.

40
Excess Iodide Induces An Acute Inhibition Of The Sodium/iodide Symporter In Thyroid Male Rat Cells By Increasing Reactive Oxygen Species
Autor(es): Arriagada A, Albornoz E, Opazo M, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza A, Bueno S, Kalergis A, Riedel C
Año: 2015.156:1540-1551.
Ref: Arriagada A, Albornoz E, Opazo M, Becerra A, Vidal G, Fardella C, Michea L, Carrasco N, Simon F, Elorza A, Bueno S, Kalergis A, Riedel C. Excess Iodide Induces an Acute Inhibition of the Sodium/Iodide Symporter in Thyroid Male Rat Cells by Increasing Reactive Oxygen Species. Endocrinology. 2015;156(4):1540-1551.

41
Human Metapneumovirus Infection Activates The Tslp Pathway That Drives Excessive Pulmonary Inflammation And Viral Replication In Mice
Autor(es): Lay M, Cespedes P, Palavecino C, Diaz R, Salazar F, Mendez G, Bueno S, Kalergis A
Año: 2015.45:1680-1695.1
Ref: Lay M, Cespedes P, Palavecino C, Diaz R, Salazar F, Mendez G, Bueno S, Kalergis A. Human metapneumovirus infection activates the TSLP pathway that drives excessive pulmonary inflammation and viral replication in mice. European Journal Of Immunology. 2015;45(6):1680-1695.

42
Herpes Simplex Virus 2 Infection: Molecular Association With Hiv And Novel Microbicides To Prevent Disease
Autor(es): Suazo Pa, Tognarelli Ei, Kalergis, Am, Gonzalez, Pa
Año: 2015.204:161-176.10.1007/s00430-014-0358-x
Ref: Suazo PA, Tognarelli EI, Kalergis, AM, Gonzalez, PA. Herpes simplex virus 2 infection: molecular association with HIV and novel microbicides to prevent disease. Medical Microbiology And Immunology. 2015;204(2):161-176.

43
Contribution Of Dendritic Cells To The Autoimmune Pathology Of Systemic Lupus Erythematosus
Autor(es): Mackern Juan , Llanos C, Riedel C, Bueno S, Kalergis A
Año: 2015.146: 497-507.
Ref: Mackern Juan , Llanos C, Riedel C, Bueno S, Kalergis A. Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus. Immunology. 2015;146(4): 497-507.

44
Immune Evasion By Herpes Simplex Virus
Autor(es): Retamal A, Suazo P, Garrido I, Kalergis A, Gonzalez P
Año: 2015.32:58-71.
Ref: Retamal A, Suazo P, Garrido I, Kalergis A, Gonzalez P. Immune evasion by herpes simplex virus. Revista Chilena De Infectología. 2015;32(1):58-71.

45
The Expression Of Rac1 And Mineralocorticoid Pathway-Dependent Genes Are Associated With Different Responses To Salt Intake
Autor(es): Alejandra Tapia-Castillo, Cristian A. Carvajal, Carmen Campino, Caroline Hill, Fidel Allende, Andrea Vecchiola, Carmen Carrasco, Rodrigo Bancalari, Carolina Valdivia, Carlos F. Lagos, Alejandro Martinez-Aguayo, Hernan Garcia, Marlene Aglony, Rene F. Baudrand, Alexis M. Kalergis, Luis F. Michea, Claudia A. Riedel, Carlos E. Fardella
Año: 2015.28:722-728.10.1093/ajh/hpu224
Ref: Alejandra Tapia-Castillo, Cristian A. Carvajal, Carmen Campino, Caroline Hill, Fidel Allende, Andrea Vecchiola, Carmen Carrasco, Rodrigo Bancalari, Carolina Valdivia, Carlos F. Lagos, Alejandro Martinez-Aguayo, Hernan Garcia, Marlene Aglony, Rene F. Baudrand, Alexis M. Kalergis, Luis F. Michea, Claudia A. Riedel, Carlos E. Fardella. The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake. American Journal Of Hypertension. 2015;28:722-728.

46
Carbon Monoxide Impairs Mitochondria-Dependent Endosomal Maturation And Antigen Presentation In Dendritic Cells
Autor(es): Riquelme S, Pogu J, Anegon I, Bueno S, Kalergis A
Año: 2015.45:3269-3288.
Ref: Riquelme S, Pogu J, Anegon I, Bueno S, Kalergis A. Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells. European Journal Of Immunology. 2015;45(12):3269-3288.

47
Elevated Il-3 And Il-12P40 Levels In The Lower Airway Of Infants With Rsv-Induced Bronchiolitis Correlate With Recurrent Wheezing
Autor(es): Bertrand P, Lay M, Piedimonte G, Brockmann P, Palavecino C, Hernandez J, Leon M, Kalergis A, Bueno S
Año: 2015.76:417-423.
Ref: Bertrand P, Lay M, Piedimonte G, Brockmann P, Palavecino C, Hernandez J, Leon M, Kalergis A, Bueno S. Elevated IL-3 and IL-12p40 levels in the lower airway of infants with RSV-induced bronchiolitis correlate with recurrent wheezing. Cytokine. 2015;76(2):417-423.

48
Central Nervous System Alterations Caused By Infection With The Human Respiratory Syncytial Virus
Autor(es): Bohmwald K, Espinoza J, Gonzalez P, Bueno S, Riedel C, Kalergis A
Año: 2014.24:407-419.
Ref: Bohmwald K, Espinoza J, Gonzalez P, Bueno S, Riedel C, Kalergis A. Central nervous system alterations caused by infection with the human respiratory syncytial virus. Reviews In Medical Virology. 2014;24(6):407-419.

49
Dietary Effect On Immunological Energetics In Mice
Autor(es): Martel S, Riquelme S, Kalergis A, Bozinovic F
Año: 2014.184:937-944.
Ref: Martel S, Riquelme S, Kalergis A, Bozinovic F. Dietary effect on immunological energetics in mice. Journal Of Comparative Physiology B-Biochemical Systemic And Environmental Physiology. 2014;184(7):937-944.

50
Gap Junction Intercellular Communications Regulate Nk Cell Activation And Modulate Nk Cytotoxic Capacity
Autor(es): Riquelme S, Kalergis A, Tittarelli A, Mendoza-Naranjo A, Farias M, Guerrero I, Ihara F, Wennerberg E, Et Al.
Año: 2014.192:1313-1319.
Ref: Riquelme S, Kalergis A, Tittarelli A, Mendoza-Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, ET AL.. Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity. Journal Of Immunology. 2014;192(3):1313-1319.

51
Respiratory Syncytial Virus Detection In Cells And Clinical Samples By Using Three New Monoclonal Antibodies
Autor(es): Gomez R, Mora J, Cortes C, Riedel C, Ferres M, Bueno S, Kalergis A
Año: 2014.86:1256-1266.
Ref: Gomez R, Mora J, Cortes C, Riedel C, Ferres M, Bueno S, Kalergis A. Respiratory syncytial virus detection in cells and clinical samples by using three new monoclonal antibodies. Journal Of Medical Virology. 2014;86(7):1256-1266.

52
Targeting Dendritic Cell Function During Systemic Autoimmunity To Restore Tolerance
Autor(es): Mackern-Oberti, J, Vega F, Llanos C, Bueno S, Kalergis A
Año: 2014.15:16381-16417.
Ref: Mackern-Oberti, J, Vega F, Llanos C, Bueno S, Kalergis A. Targeting dendritic cell function during systemic autoimmunity to restore tolerance. International Journal Of Molecular Sciences. 2014;15(9):16381-16417.

53
Modulation Of Host Adaptive Immunity By Hrsv Proteins
Autor(es): Espinoza J, Bohmwald K, Cespedes P, Riedel C, Bueno S, Kalergis A
Año: 2014.5:740-751.
Ref: Espinoza J, Bohmwald K, Cespedes P, Riedel C, Bueno S, Kalergis A. Modulation of host adaptive immunity by hRSV proteins. Virulence. 2014;5(7):740-751.

54
High Sodium Intake Is Associated With Increased Glucocorticoid Production, Insulin Resistance And Metabolic Syndrome
Autor(es): Baudrand R, Campino C, Carvajal C, Olivieri O, Guidi G, Faccini G, Voehringer P, Cerda J, Owen G, Kalergis A, Fardella C
Año: 2014.80:677-684.
Ref: Baudrand R, Campino C, Carvajal C, Olivieri O, Guidi G, Faccini G, Voehringer P, Cerda J, Owen G, Kalergis A, Fardella C. High sodium intake is associated with increased glucocorticoid production, insulin resistance and metabolic syndrome. Clinical Endocrinology. 2014;80(5):677-684.

55
Immunization With A Recombinant Bacillus Calmette-Guérin Strain Confers Protective Th1 Immunity Against The Human Metapneumovirus
Autor(es): Palavecino C, Cespedes P, Gomez R, Kalergis A, Bueno S
Año: 2014.192:214-223.
Ref: Palavecino C, Céspedes P, Gomez R, Kalergis A, Bueno S. Immunization with a recombinant bacillus calmette-guérin strain confers protective Th1 immunity against the human metapneumovirus. Journal Of Immunology. 2014;192(1):214-223.

56
Surface Expression Of The Hrsv Nucleoprotein Impairs Immunological Synapse Formation With T Cells
Autor(es): Cespedes P, Bueno S, Ramireza B, Gomez R, Riquelme S, Palavecino C, Mackern-Oberti J, Mora J, Kalergis A, Depoil D, Sacristan C, Et Al.
Año: 2014.111:E3214-E3223.
Ref: Cespedes P, Bueno S, Ramireza B, Gomez R, Riquelme S, Palavecino C, Mackern-Oberti J, Mora J, Kalergis A, Depoil D, Sacristan C, ET AL.. Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2014;111(31):E3214-E3223.

57
Heme Oxygenase-1 As A Target For The Design Of Gene And Pharmaceutical Therapies For Autoimmune Diseases
Autor(es): Mackern-Oberti J, Riquelme S, Llanos C, Schmidt C, Simon T, Anegon I, Jara E, Riedel C, Bueno S, Kalergis A
Año: 2014.14:218-235.
Ref: Mackern-Oberti J, Riquelme S, Llanos C, Schmidt C, Simon T, Anegon I, Jara E, Riedel C, Bueno S, Kalergis A. Heme Oxygenase-1 as a Target for the Design of Gene and Pharmaceutical Therapies for Autoimmune Diseases. Current Gene Therapy. 2014;14(3):218-235.

58
Independent Anti-Angiogenic Capacities Of Coagulation Factors X And Xa
Autor(es): Lange S, Gonzalez I, Pinto M, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henriquez S, Velasquez E, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo K, Kalergis A, Pererira K, Mendoza C, Saez C, Kato S, Cuello M, Parborell F, Irusta G, Palma V, Allende M, Owen G
Año: 2014.229:1673-1680.
Ref: Lange S, Gonzalez I, Pinto M, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henríquez S, Velasquez E, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo K, Kalergis A, Pererira K, Mendoza C, Saez C, Kato S, Cuello M, Parborell F, Irusta G, Palma V, Allende M, Owen G. Independent Anti-Angiogenic Capacities of Coagulation Factors X and Xa. Journal Of Cellular Physiology. 2014;229(11):1673-1680.

59
Induction Of Protective Effector Immunity To Prevent Pathogenesis Caused By The Respiratory Syncytial Virus. Implications On Therapy And Vaccine Design
Autor(es): Espinoza Ja, Bueno Sm, Riedel Ca, Kalergis Am
Año: 2014.1:1-12.10.1111/imm.12313
Ref: Espinoza JA, Bueno SM, Riedel CA, Kalergis AM. Induction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine design. Immunology. 2014;1(143):1-12.

60
Respiratory Syncytial Virus: Pathology, Therapeutic Drugs And Prophylaxis
Autor(es): Gomez R, Guisle-Marsollier I, Bohmwald K, Bueno S, Kalergis A
Año: 2014.162:237-247.
Ref: Gomez R, Guisle-Marsollier I, Bohmwald K, Bueno S, Kalergis A. Respiratory Syncytial Virus: Pathology, therapeutic drugs and prophylaxis. Immunology Letters. 2014;162(1):237-247.

61
Spironolactone Decreases Doca-Salt-Induced Organ Damage By Blocking The Activation Of T Helper 17 And The Downregulation Of Regulatory T Lymphocytes
Autor(es): Amador C, Barrientos V, Pena J, Herrada A, Gonzalez M, Valdes S, Carrasco L, Kalergis A, Et Al.
Año: 2014.63:797-803.
Ref: Amador C, Barrientos V, Pena J, Herrada A, Gonzalez M, Valdes S, Carrasco L, Kalergis A, ET AL.. Spironolactone Decreases DOCA-Salt-Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes. Hypertension. 2014;63(4):797-803.

62
A Novel Live Vector Group A Streptococcal Emm Type 9 Vaccine Delivered Intranasally Protects Mice Against Challenge Infection With Emm Type 9 Group A Streptococci
Autor(es): Wozniak A, Garcia P, Geoffroy E, Aguirre D, Gonzalez S, Sarno V, Vera A, Salazar-Echegarai F, Bueno S, Kalergis A, Dale J
Año: 2014.21:1343-1349.
Ref: Wozniak A, Garcia P, Geoffroy E, Aguirre D, Gonzalez S, Sarno V, Vera A, Salazar-Echegarai F, Bueno S, Kalergis A, Dale J. A Novel Live Vector Group A Streptococcal emm Type 9 Vaccine Delivered Intranasally Protects Mice against Challenge Infection with emm Type 9 Group A Streptococci. Clinical And Vaccine Immunology. 2014;21(9):1343-1349.

63
Human Metapneumovirus Keeps Dendritic Cells From Priming Antigen-Specific Naive T Cells
Autor(es): Cespedes P, Gonzalez P, Kalergis A
Año: 2013.139:366-376.
Ref: Cespedes P, Gonzalez P, Kalergis A. Human metapneumovirus keeps dendritic cells from priming antigen-specific naive T cells. Immunology. 2013;139(3):366-376.

64
Carbon Monoxide Decreases Endosome-Lysosome Fusion And Inhibits Soluble Antigen Presentation By Dendritic Cells To T Cells
Autor(es): Riquelme S, Carreno L, Bueno S, Kalergis A, Tardif V, Remy S, Cortes C, Simon T, Et Al.
Año: 2013.43:2832-2844.
Ref: Riquelme S, Carreno L, Bueno S, Kalergis A, Tardif V, Remy S, Cortes C, Simon T, ET AL.. Carbon monoxide decreases endosome-lysosome fusion and inhibits soluble antigen presentation by dendritic cells to T cells. European Journal Of Immunology. 2013;43(11):2832-2844.

65
Advances In Understanding Respiratory Syncytial Virus Infection In Airway Epithelial Cells And Consequential Effects On The Immune Response
Autor(es): Lay M, Gonzalez P, Leon M, Cespedes P, Bueno S, Riedel C, Kalergis A
Año: 2013.15:230-242.
Ref: Lay M, Gonzalez P, Leon M, Cespedes P, Bueno S, Riedel C, Kalergis A. Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response. Microbes And Infection. 2013;15(3):230-242.

66
Immune System Alterations By Aldosterone During Hypertension: From Clinical Observations To Genomic And Non-Genomic Mechanisms Leading To Vascular Damage
Autor(es): Munoz N, Barake M, Letelier N, Campino C, Fardella C, Kalergis A
Año: 2013.13:1035-1046.
Ref: Munoz N, Barake M, Letelier N, Campino C, Fardella C, Kalergis A. Immune System Alterations by Aldosterone During Hypertension: From Clinical Observations to Genomic and Non-Genomic Mechanisms Leading to Vascular Damage. Current Molecular Medicine. 2013;13(6):1035-1046.

67
Age-Related Changes In 11 Beta-Hydroxysteroid Dehydrogenase Type 2 Activity In Normotensive Subjects
Autor(es): Campino C, Martinez-Aguayo A, Baudrand R, Carvajal C, Aglony M, Garcia H, Padilla O, Kalergis A, Fardella C
Año: 2013.26:481-487.
Ref: Campino C, Martinez-Aguayo A, Baudrand R, Carvajal C, Aglony M, Garcia H, Padilla O, Kalergis A, Fardella C. Age-Related Changes in 11 beta-Hydroxysteroid Dehydrogenase Type 2 Activity in Normotensive Subjects. American Journal Of Hypertension. 2013;26(4):481-487.

68
Understanding Respiratory Syncytial Virus Infection To Improve Treatment And Immunity
Autor(es): Carreno L, Bueno S, Riedel C, Kalergis A, Gonzalez P
Año: 2013.13:1122-1139.
Ref: Carreno L, Bueno S, Riedel C, Kalergis A, Gonzalez P. Understanding Respiratory Syncytial Virus Infection to Improve Treatment and Immunity. Current Molecular Medicine. 2013;13(7):1122-1139.

69
Gestational Hypothyroidism Increases The Severity Of Experimental Autoimmune Encephalomyelitis In Adult Offspring
Autor(es): Albornoz Ea, Carreno Lj, Cortes Cm, Gonzalez Pa, Cisternas Pa, Cautivo Km, Catalan Tp, Opazo Mc, Eugenin Ea, Berman Jw, Bueno Sm, Kalergis Am, Riedel Ca
Año: 2013.12:1627-37.10.1089/thy.2012.0401
Ref: Albornoz EA, Carreño LJ, Cortes CM, Gonzalez PA, Cisternas PA, Cautivo KM, Catalán TP, Opazo MC, Eugenin EA, Berman JW, Bueno SM, Kalergis AM, Riedel CA. Gestational hypothyroidism increases the severity of experimental autoimmune encephalomyelitis in adult offspring. Thyroid. 2013;12(23):1627-37.

70
Immunological Vulnerability And Adjustments To Environmental Thermal Variability
Autor(es): Bozinovic F, Catalan T, Kalergis A
Año: 2013.86:475-483.
Ref: Bozinovic F, Catalan T, Kalergis A. Immunological vulnerability and adjustments to environmental thermal variability. Revista Chilena De Historia Natural. 2013;86(4):475-483.

71
Gene Elements That Regulate Streptococcus Pneumoniae Virulence And Immunity Evasion
Autor(es): Nieto P, Riquelme S, Riedel C, Kalergis A, Bueno S
Año: 2013.13:51-64.
Ref: Nieto P, Riquelme S, Riedel C, Kalergis A, Bueno S. Gene Elements that Regulate Streptococcus pneumoniae Virulence and Immunity Evasion. Current Gene Therapy. 2013;13(1):51-64.

72
Chromosomal Excision Of A New Pathogenicity Island Modulates Salmonella Virulence In Vivo
Autor(es): Tobar He, Salazar-Echegarai Fj, Nieto Pa, Palavecino Ce, Sebastian Vp, Sebastian Vp, Riedel Ca, Kalergis Am, Bueno Sm
Año: 2013.4:240-249.
Ref: Tobar HE, Salazar-Echegarai FJ, Nieto PA, Palavecino CE, Sebastian VP, Sebastian VP, Riedel CA, Kalergis AM, Bueno SM. Chromosomal excision of a new pathogenicity island modulates Salmonella virulence in vivo. Current Gene Therapy. 2013;4(13):240-249.

73
Modulation Of Tumor Immunity By Soluble And Membrane-Bound Molecules At The Immunological Synapse
Autor(es): Gonzalez P, Carreno L, Cespedes P, Bueno S, Riedel C, Kalergis A
Año: 2013.2013:Art. 450291-..
Ref: Gonzalez P, Carreno L, Cespedes P, Bueno S, Riedel C, Kalergis A. Modulation of Tumor Immunity by Soluble and Membrane-Bound Molecules at the Immunological Synapse. Clinical & Developmental Immunology. 2013;2013:Art. 450291-..

74
Tolerogenic Dendritic Cells As A Therapy For Treating Lupus.
Autor(es): Llanos C, Mackern-Oberti Jp, Vega F, Jacobell Sh, Kalergis Am
Año: 2013.:237-245.
Ref: Llanos C, Mackern-Oberti JP, Vega F, Jacobell SH, Kalergis AM. Tolerogenic dendritic cells as a therapy for treating lupus. . Clinical Immunology. 2013;(148):237-245.

75
Carbon Monoxide Exposure Improves Immune Function In Lupus-Prone Mice
Autor(es): Mackern J, Llanos C, Carreno L, Riquelme S, Anegon I, Kalergis A, Anegon I
Año: 2013.140:123-132.
Ref: Mackern J, Llanos C, Carreno L, Riquelme S, Anegon I, Kalergis A, Anegon I. Carbon monoxide exposure improves immune function in lupus-prone mice. Immunology. 2013;140(1):123-132.

76
Tolerogenic Dendritic Cells As A Therapy For Treating Lupus
Autor(es): Llanos C, Mackern-Oberti J, Vega F, Kalergis A
Año: 2013.148:237-245.
Ref: Llanos C, Mackern-Oberti J, Vega F, Kalergis A. Tolerogenic dendritic cells as a therapy for treating lupus. Clinical Immunology. 2013;148(2):237-245.

77
Modulation Of Tumor Immunity By Soluble And Membrane-Bound Molecules At The Immunological Synapse
Autor(es): Gonzalez Pa, Carreno Lj, Cespedes Pf, Bueno Sm, Riedel Ca, Kalergis Am
Año: 2013.2013:450291-450301.10.1155/2013/450291.
Ref: González PA, Carreño LJ, Céspedes PF, Bueno SM, Riedel CA, Kalergis AM. Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse . Clinical & Developmental Immunology. 2013;2013(2013):450291-450301.

78
Role Of Salmonella Enterica Exposure In Chilean Crohn's Disease Patients
Autor(es): Alvarez-Lobos M, Pizarro D, Espinoza A, Sebastian V, Alvarado J, Ibanez P, Quintana C, Diaz O, Kalergis Am, Bueno Sm
Año: 2013.19:5855-5862.
Ref: Alvarez-Lobos M, Pizarro D, Espinoza A, Sebastian V, Alvarado J, Ibanez P, Quintana C, Diaz O, Kalergis AM, Bueno SM. Role of Salmonella enterica exposure in Chilean Crohn's disease patients. World Journal Of Gastroenterology. 2013;19(35):5855-5862.

79
Gestational Hypothyroidism Increases The Severity Of Experimental Autoimmune Encephalomyelitis In Adult Offspring
Autor(es): Carreno L, Cortes C, Gonzalez P, Cisternas P, Cautivo K, Catalan T, Bueno S, Kalergis A, Riedel C, Et Al.
Año: 2013.23:1627-1637.
Ref: Carreno L, Cortes C, Gonzalez P, Cisternas P, Cautivo K, Catalan T, Bueno S, Kalergis A, Riedel C, ET AL.. Gestational Hypothyroidism Increases the Severity of Experimental Autoimmune Encephalomyelitis in Adult Offspring. Thyroid. 2013;23(12):1627-1637.

80
Impaired Learning Resulting From Respiratory Syncytial Virus Infection
Autor(es): Espinoza Janyra A, Bohmwald Karen, Cespedes Pablo F, Gomez Roberto S, Riquelme Sebastian A, Cortes Claudia M, Valenzuela Javier A, Sandoval Rodrigo A, Pancetti Floria C, Bueno Susan M, Riedel Claudia A, Kalergis Alexis M
Año: 2013.110:9112-9117.
Ref: Espinoza Janyra A, Bohmwald Karen, Cespedes Pablo F, Gomez Roberto S, Riquelme Sebastian A, Cortes Claudia M, Valenzuela Javier A, Sandoval Rodrigo A, Pancetti Floria C, Bueno Susan M, Riedel Claudia A, Kalergis Alexis M. Impaired learning resulting from Respiratory Syncytial Virus infection. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2013;110(22):9112-9117.

81
Understanding Respiratory Syncytial Virus Infection To Improve Treatment And Immunity
Autor(es): Gonzalez Pa, Carreno Lj, Bueno Sm, Riedel Ca, Kalergis Am
Año: 2013.7:1122-1139.
Ref: González PA, Carreño LJ, Bueno SM, Riedel CA, Kalergis AM. Understanding respiratory syncytial virus infection to improve treatment and immunity. Current Molecular Medicine. 2013;7(13):1122-1139.

82
Fc Gamma Riib And Baff Differentially Regulate Peritoneal B1 Cell Survival
Autor(es): Vesely M, Schwartz M , Bermejo D, Montes C, Cautivo K, Kalergis A, Rawlings D, Acosta E, Gruppi A
Año: 2012.188:4792-4800.
Ref: Vesely M, Schwartz M , Bermejo D, Montes C, Cautivo K, Kalergis A, Rawlings D, Acosta E, Gruppi A. Fc gamma RIIb and BAFF Differentially Regulate Peritoneal B1 Cell Survival. Journal Of Immunology. 2012;188(10):4792-4800.

83
11 Beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms And Activity In A Chilean Essential Hypertensive And Normotensive Cohort
Autor(es): Campino C, Quinteros H, Owen G, Carvajal C, Morales M, Olivieri O , Guidi G , Faccini G , Pasini F, Baudrand R , Padilla O, Valdivia C , Thichauer J , Lagos C, Kalergis A, Fardella C
Año: 2012.25:597-603.
Ref: Campino C, Quinteros H, Owen G, Carvajal C, Morales M, Olivieri O , Guidi G , Faccini G , Pasini F, Baudrand R , Padilla O, Valdivia C , Thichauer J , Lagos C, Kalergis A, Fardella C. 11 beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms and Activity in a Chilean Essential Hypertensive and Normotensive Cohort. American Journal Of Hypertension. 2012;25(5):597-603.

84
Bone Marrow Stromal Cells Modulate Mouse Ent1 Activity And Protect Leukemia Cells From Cytarabine Induced Apoptosis
Autor(es): Macanas P , Leisewitz A , Broekhuizen R , Cautivo K , Barriga F, Leisewitz F, Gidi V, Riquelme E , Montecinos V, Swett P , Besa P , Ramirez P , Ocqueteau M, Kalergis A, Holt M , Rettig M, Dipersio J, Nervi B
Año: 2012.7:Art.e37203-..
Ref: Macanas P , Leisewitz A , Broekhuizen R , Cautivo K , Barriga F, Leisewitz F, Gidi V, Riquelme E , Montecinos V, Swett P , Besa P , Ramirez P , Ocqueteau M, Kalergis A, Holt M , Rettig M, DiPersio J, Nervi B . Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis. Plos One. 2012;7(5):Art.e37203-..

85
M-Protein Gene-Type Distribution And Hyaluronic Acid Capsule In Group A Streptococcus Clinical Isolates In Chile: Association Of Emm Gene Markers With Csrr Alleles
Autor(es): Wozniak A , Rojas P , Rodriguez C , Undabarrena A , Garate C , Riedel I, Roman J, Kalergis A, Garcia P
Año: 2012.140:1286-1295.
Ref: Wozniak A , Rojas P , Rodriguez C , Undabarrena A , Garate C , Riedel I, Roman J, Kalergis A, Garcia P . M-protein gene-type distribution and hyaluronic acid capsule in group A Streptococcus clinical isolates in Chile: association of emm gene markers with csrR alleles. Epidemiology And Infection. 2012;140(7):1286-1295.

86
Respiratory Syncytial Virus Infection And Immunity
Autor(es): Gonzalez P, Bueno S, Carreno L, Riedel C, Kalergis A
Año: 2012.22:230-244.
Ref: Gonzalez P, Bueno S, Carreno L, Riedel C, Kalergis A. Respiratory syncytial virus infection and immunity. Reviews In Medical Virology. 2012;22(4):230-244.

87
Phenotype And Genotype Of Thiopurine Methyltransferase In Chilean Individuals
Autor(es): Jorquera A , Solari S , Vollrath V, Guerra I , Chianale J, Cofre C, Kalergis A , Ibanez P , Bueno S , Alvarez M
Año: 2012.140:889-895.
Ref: Jorquera A , Solari S , Vollrath V, Guerra I , Chianale J, Cofre C, Kalergis A , Ibanez P , Bueno S , Alvarez M . Phenotype and genotype of thiopurine methyltransferase in Chilean individuals. Revista Medica De Chile. 2012;140(7):889-895.

88
Mechanisms Used By Virulent Salmonella To Impair Dendritic Cell Function And Evade Adaptive Immunity
Autor(es): Bueno S, Riquelme S, Riedel C, Kalergis A
Año: 2012.137:28-36.
Ref: Bueno S, Riquelme S, Riedel C, Kalergis A. Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity. Immunology. 2012;137(1):28-36.

89
Interplay Between Thermal And Immune Ecology: Effect Of Environmental Temperature On Insect Immune Response And Energetic Costs After An Immune Challenge
Autor(es): Catalan T, Wozniak A , Niemeyer H, Kalergis A, Bozinovic F
Año: 2012.58:310-317.
Ref: Catalan T, Wozniak A , Niemeyer H, Kalergis A, Bozinovic F. Interplay between thermal and immune ecology: Effect of environmental temperature on insect immune response and energetic costs after an immune challenge. Journal Of Insect Physiology. 2012;58(3):310-317.

90
Haem Oxygenase 1 Expression Is Altered In Monocytes From Patients With Systemic Lupus Erythematosus
Autor(es): Herrada A, Llanos C, Mackern J, Carreno L, Henriquez C , Gomez R, Gutierrez M, Anegon I , Jacobelli S, Kalergis A
Año: 2012.136:414-424.
Ref: Herrada A, Llanos C, Mackern J, Carreno L, Henriquez C , Gomez R, Gutierrez M, Anegon I , Jacobelli S, Kalergis A. Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus. Immunology. 2012;136(4):414-424.

91
Igg Keeps Virulent Salmonella From Evading Dendritic Cell Uptake
Autor(es): Riquelme S, Bueno S, Kalergis A
Año: 2012.136:291-305.
Ref: Riquelme S, Bueno S, Kalergis A. IgG keeps virulent Salmonella from evading dendritic cell uptake. Immunology. 2012;136(3):291-305.

92
Interplay Between Behavioural Thermoregulation And Immune Response In Mealworms
Autor(es): Catalan T, Niemeyer H, Kalergis A, Bozinovic F
Año: 2012.58:1450-1455.
Ref: Catalan T, Niemeyer H, Kalergis A, Bozinovic F. Interplay between behavioural thermoregulation and immune response in mealworms. Journal Of Insect Physiology. 2012;58(11):1450-1455.

93
Hypothyroidism In The Adult Rat Causes Incremental Changes In Brain-Derived Neurotrophic Factor, Neuronal And Astrocyte Apoptosis, Gliosis, And Deterioration Of Postsynaptic Density
Autor(es): Cortes C , Eugenin E , Aliaga E , Carreno L, Bueno S, Gonzalez P, Gayol S , Naranjo D, Noches V , Marassi M, Rosenthal D , Jadue C, Ibarra P , Keitel C, Wohllk N , Court F, Kalergis A, Riedel C
Año: 2012.22:951-963.
Ref: Cortes C , Eugenin E , Aliaga E , Carreno L, Bueno S, Gonzalez P, Gayol S , Naranjo D, Noches V , Marassi M, Rosenthal D , Jadue C, Ibarra P , Keitel C, Wohllk N , Court F, Kalergis A, Riedel C. Hypothyroidism in the Adult Rat Causes Incremental Changes in Brain-Derived Neurotrophic Factor, Neuronal and Astrocyte Apoptosis, Gliosis, and Deterioration of Postsynaptic Density. Thyroid. 2012;22(9):951-963.

94
Igg Keeps Virulent Salmonella From Evading Dendritic Cell Uptake
Autor(es): Riquelme Sa, Bueno Sm, Kalergis Am
Año: 2012.3:291-305.10.1111/j.1365-2567.2012.03578
Ref: Riquelme SA, Bueno SM, Kalergis AM. IgG keeps virulent Salmonella from evading dendritic cell uptake. Immunology. 2012;3(136):291-305.

95
11Beta-Hydroxysteroid Dehydrogenase Type 2 Polymorphisms And Activity In A Chilean Essential Hypertensive And Normotensive Cohort
Autor(es): Carmen Campino, Hector Quinteros, Gareth I. Owen, Cristian A. Carvajal, Mauricio Morales, Oliviero Olivieri, Giancesare Guidi, Giovanni Faccini, Francesco Pasini, Rene Baudrand, Oslando Padilla, Carolina Valdivia, Juan Tichauer, Carlos F. Lagos, Alexis M. Kalergis, Carlos E. Fardella
Año: 2012.25:597-603.10.1038/ajh.2011.263
Ref: Carmen Campino, Hector Quinteros, Gareth I. Owen, Cristian A. Carvajal, Mauricio Morales, Oliviero Olivieri, Giancesare Guidi, Giovanni Faccini, Francesco Pasini, Rene Baudrand, Oslando Padilla, Carolina Valdivia, Juan Tichauer, Carlos F. Lagos, Alexis M. Kalergis, Carlos E. Fardella. 11beta-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort. American Journal Of Hypertension. 2012;25:597-603.

96
Contribution Of Dendritic Cell/t Cell Interactions To Triggering And Maintaining Autoimmunity
Autor(es): Llanos C , Carreno L, , Kalergis Am
Año: 2011.44:53-61.
Ref: Llanos C , Carreno L, , Kalergis AM . Contribution of dendritic cell/T cell interactions to triggering and maintaining autoimmunity. Biological Research. 2011;44(1):53-61.

97
Aldosterone As A Modulator Of Immunity: Implications In The Organ Damage
Autor(es): Herrada A , Campino C , Amador C, Michea L, Fardella C, Kalergis A
Año: 2011.29:1684-1692.
Ref: Herrada A , Campino C , Amador C, Michea L, Fardella C, Kalergis A. Aldosterone as a modulator of immunity: implications in the organ damage. Journal Of Hypertension. 2011;29(9):1684-1692.

98
Genetic And Pharmacological Modulation Of Dendritic Cell-T Cell Interactions As A Therapeutic Strategy For Systemic Lupus Erythematosus
Autor(es): Llanos C, Carreno L, Gutierrez M, Riedel C, Jacobelli S, Kalergis A
Año: 2011.11:544-553.
Ref: Llanos C, Carreño L, Gutierrez M, Riedel C, Jacobelli S, Kalergis A. Genetic and pharmacological modulation of dendritic Cell-T Cell interactions as a therapeutic strategy for systemic lupus erythematosus. Current Gene Therapy. 2011;11(6):544-553.

99
Excision Of An Unstable Pathogenicity Island In Salmonella Enterica Serovar Enteritidis Is Induced During Infection Of Phagocytic Cells
Autor(es): Quiroz T, Nieto P, Tobar H, Salazar F, Lizana R, Quezada C, Santiviago C, Araya D, Riedel C, Kalergis A, Bueno S
Año: 2011.6:Art. e26031-..
Ref: Quiroz T, Nieto P, Tobar H, Salazar F, Lizana R, Quezada C, Santiviago C, Araya D, Riedel C, Kalergis A, Bueno S. Excision of an Unstable Pathogenicity Island in Salmonella enterica Serovar Enteritidis Is Induced during Infection of Phagocytic Cells. Plos One. 2011;6(10):Art. e26031-..

100
Infection Of Human Monocyte-Derived Dendritic Cells By Andes Hantavirus Enhances Proinflammatory State, The Secretion Of Active Mmp-9 And Indirectly Enhances Endothelial Permeability
Autor(es): Marsac D , Garcia S , Fournet A , Aguirre A, Pino K , Ferres M, Kalergis A , Lopez-Lastra M, Veas F
Año: 2011.8:Art. 223-..
Ref: Marsac D , Garcia S , Fournet A , Aguirre A, Pino K , Ferres M, Kalergis A , Lopez-Lastra M, Veas F . Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances proinflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability. Virology Journal. 2011;8:Art. 223-..

101
Evasion Of Host Immunity By Virulent Salmonella: Implications For Vaccine Design
Autor(es): Riquelme S, Wozniak A , Kalergis A, Bueno S
Año: 2011.18:5666-5675.
Ref: Riquelme S, Wozniak A , Kalergis A, Bueno S. Evasion of Host Immunity by Virulent Salmonella: Implications for Vaccine Design. Current Medicinal Chemistry. 2011;18(36):5666-5675.

102
A De Novo Unequal Cross-Over Mutation Between Cyp11B1 And Cyp11B2 Genes Causes Familial Hyperaldosteronism Type I
Autor(es): Carvajal C , Stehr C , Gonzalez P, Riquelme E, Montero T , Santos M, Kalergis A , Fardella C
Año: 2011.34:140-144.
Ref: Carvajal C , Stehr C , Gonzalez P, Riquelme E, Montero T , Santos M, Kalergis A , Fardella C . A de novo unequal cross-over mutation between CYP11B1 and CYP11B2 genes causes familial hyperaldosteronism type I. Journal Of Endocrinological Investigation. 2011;34(2):140-144.

103
Functional Gap Junctions Accumulate At The Immunological Synapse And Contribute To T Cell Activation
Autor(es): Mendoza A , Bouma G , Pereda C , Ramirez M, Webb K, Tittarelli A , Lopez M, Kalergis A, Thrasher A, Becker D, Salazar F
Año: 2011.187:3121-3132.
Ref: Mendoza A , Bouma G , Pereda C , Ramirez M, Webb K, Tittarelli A , Lopez M, Kalergis A, Thrasher A, Becker D, Salazar F . Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation. Journal Of Immunology. 2011;187(6):3121-3132.

104
Increased Urinary Glucocorticoid Metabolites Are Associated With Metabolic Syndrome, Hypoadiponectinemia, Insulin Resistance And Beta Cell Dysfunction
Autor(es): Baudrand R , Campino C, Carvajal C, Olivieri O, Guidi G , Faccini G , Sateler J , Cornejo J , San Martin B, Dominguez J, Cerda J , Mosso L, Owen G, Kalergis A, Fardella C
Año: 2011.76:1575-1581.
Ref: Baudrand R , Campino C, Carvajal C, Olivieri O, Guidi G , Faccini G , Sateler J , Cornejo J , San Martin B, Dominguez J, Cerda J , Mosso L, Owen G, Kalergis A, Fardella C. Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and beta cell dysfunction. Steroids. 2011;76(14):1575-1581.

105
Local Cytokine Response Upon Respiratory Syncytial Virus Infection
Autor(es): Bueno S, Gonzalez P , Riedel C, Carreno L , Vasquez A, Kalergis A
Año: 2011.136:122-129.
Ref: Bueno S, Gonzalez P , Riedel C, Carreno L , Vasquez A, Kalergis A . Local cytokine response upon respiratory syncytial virus infection. Immunology Letters. 2011;136(2):122-129.

106
Modulation Of The Dendritic Cell-T-Cell Synapse To Promote Pathogen Immunity And Prevent Autoimmunity
Autor(es): Carreno L , Gonzalez P, Bueno S, Riedel C, Kalergis A
Año: 2011.3:6-11.
Ref: Carreno L , Gonzalez P, Bueno S, Riedel C, Kalergis A . Modulation of the dendritic cell-T-cell synapse to promote pathogen immunity and prevent autoimmunity . Journal Of Immunotherapy. 2011;3(4):6-11.

107
Análisis De Los Fenotipos Y Genotipos De Resistencia A Eritromicina Y Clindamicina En Cepas De Streptococcus Pyogenes Aisladas En Chile En Un Período De 10 Años
Autor(es): Rodriguez C , Rojas P , Wozniak A , Kalergis A, Ceron I , Riedel I, Roman J, Villarroel L, Berrios X , Bavestrello L , Garcia P
Año: 2011.139:11143-1149.
Ref: Rodriguez C , Rojas P , Wozniak A , Kalergis A, Ceron I , Riedel I, Roman J, Villarroel L, Berrios X , Bavestrello L , Garcia P . Análisis de los fenotipos y genotipos de resistencia a eritromicina y clindamicina en cepas de Streptococcus pyogenes aisladas en Chile en un período de 10 años. Revista Medica De Chile. 2011;139(9):11143-1149.

108
Aldosterone Promotes Autoimmune Damage By Enhancing Th17-Mediated Immunity
Autor(es): Herrada Aa, Contreras Fj, Marini Np, Amador Ca, Gonzalez Pa, Cortes Cm, Riedel Ca, Carvajal Ca, Figueroa F, Michea Lf, Fardella Ce, Kalergis Am
Año: 2010.184:191-202.
Ref: Herrada AA, Contreras FJ, Marini NP, Amador CA, González PA, Cortés CM, Riedel CA, Carvajal CA, Figueroa F, Michea LF, Fardella CE, Kalergis AM. Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity. Journal Of Immunology. 2010;184(1):191-202.

109
Salmonella Pathogenicity Island 1 Differentially Modulates Bacterial Entry To Dendritic And Non-Phagocytic Cells
Autor(es): Bueno Sm, Wozniak A, Leiva Ed, Riquelme Sa, Carreno Lj, Hardt Wd, Riedel Ca, Kalergis Am
Año: 2010.130:273-287.
Ref: Bueno SM, Wozniak A, Leiva ED, Riquelme SA, Carreño LJ, Hardt WD, Riedel CA, Kalergis AM. Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non-phagocytic cells. Immunology. 2010;130(2):273-287.

110
Virulence Mechanisms Displayed By Salmonella To Impair Dendritic Cell Function
Autor(es): Bueno Sm, Riedel Ca, Carreno Lj, Kalergis Am
Año: 2010.17:1156-1166.
Ref: Bueno SM, Riedel CA, Carreño LJ, Kalergis AM. Virulence Mechanisms Displayed by Salmonella to Impair Dendritic Cell Function. Current Medicinal Chemistry. 2010;17(12):1156-1166.

111
Emerging Evidence For The Role Of Neurotransmitters In The Modulation Of T Cell Responses To Cognate Ligands
Autor(es): Pacheco R, Riquelme E, Kalergis A
Año: 2010.10:65-83.
Ref: Pacheco R, Riquelme E, Kalergis A. Emerging evidence for the role of neurotransmitters in the modulation of T cell responses to cognate ligands. Central Nervous System Agents In Medicinal Chemistry. 2010;10(1):65-83.

112
Research Priorities For Neglected Infectious Diseases In Latin America And The Caribbean Region
Autor(es): Dujardin Jc, Herrera S, Do Rosario V, Arevalo J , Boelaert M , Carrasco Hj, Correa R, Garcia L , Gotuzzo E, Gyorkos Tw, Kalergis A, Kouri G, Larraga V, Lutumba P , Garcia Ma, Manrique Pc, Modabber F, Nieto A, Pluschke G, Robello C, De Arias Ar, Rumbo M, Preciado Jis , Sundar S, Torres J , Torrico F, Van Der Stuyft P, Victoir K , Olesen Of
Año: 2010.4:Art. e780-..
Ref: Dujardin JC, Herrera S, do Rosario V, Arevalo J , Boelaert M , Carrasco HJ, Correa R, Garcia L , Gotuzzo E, Gyorkos TW, Kalergis A, Kouri G, Larraga V, Lutumba P , Garcia MA, Manrique PC, Modabber F, Nieto A, Pluschke G, Robello C, de Arias AR, Rumbo M, Preciado JIS , Sundar S, Torres J , Torrico F, Van der Stuyft P, Victoir K , Olesen OF. Research Priorities for Neglected Infectious Diseases in Latin America and the Caribbean Region. Plos Neglected Tropical Diseases. 2010;4(10):Art. e780-..

113
11 Beta-Hydroxysteroid Dehydrogenase Type-2 And Type-1 (11 Beta-Hsd2 And 11 Beta-Hsd1) And 5 Beta-Reductase Activities In The Pathogenia Of Essential Hypertension
Autor(es): Campino C, Carvajal Ca, Cornejo J, San Martin B, Olivieri O, Guidi G, Faccini G, Pasini F, Sateler J, Baudrand R, Mosso L, Owen Gi, Kalergis Am, Padilla O, Fardella Ce
Año: 2010.37:106-114.
Ref: Campino C, Carvajal CA, Cornejo J, San Martín B, Olivieri O, Guidi G, Faccini G, Pasini F, Sateler J, Baudrand R, Mosso L, Owen GI, Kalergis AM, Padilla O, Fardella CE. 11 beta-hydroxysteroid dehydrogenase type-2 and type-1 (11 beta-HSD2 and 11 beta-HSD1) and 5 beta-reductase activities in the pathogenia of essential hypertension. Endocrine. 2010;37(1):106-114.

114
B Cells From Rheumatoid Arthritis Patients Show Important Alterations In The Expression Of Cd86 And Fc Gamma Riib, Which Are Modulated By Anti-Tumor Necrosis Factor Therapy
Autor(es): Catalan D, Aravena O, Sabugo F, Wurmann P, Soto L, Kalergis Am, Cuchacovich M, Aguillon Jc
Año: 2010.12:1-11.
Ref: Catalán D, Aravena O, Sabugo F, Wurmann P, Soto L, Kalergis AM, Cuchacovich M, Aguillon JC. B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and Fc gamma RIIb, which are modulated by anti-tumor necrosis factor therapy. Arthritis Research & Therapy. 2010;12(2):1-11.

115
Efficient Lung Recruitment Of Respiratory Syncytial Virus-Specific Th1 Cells Induced By Recombinant Bacillus Calmette-Guerin Promotes Virus Clearance And Protects From Infection
Autor(es): Cautivo K, Bueno S, Cortes Cm, Wozniak A, Riedel C, Kalergis Am
Año: 2010.185:7633-7645.
Ref: Cautivo K, Bueno S, Cortes CM, Wozniak A, Riedel C, Kalergis AM . Efficient Lung Recruitment of Respiratory Syncytial Virus-Specific Th1 Cells Induced by Recombinant Bacillus Calmette-Guerin Promotes Virus Clearance and Protects from Infection . Journal Of Immunology. 2010;185(12):7633-7645.

116
T-Cell Antagonism By Short Half-Life Pmhc Ligands Can Be Mediated By An Efficient Trapping Of T-Cell Polarization Toward The Apc
Autor(es): Carreno L, Riquelme Em, Gonzalez Pa, Espagnolle N, Riedel Ca, Valitutti S, Kalergis A
Año: 2010.107:210-215.
Ref: Carreño L, Riquelme EM, González PA, Espagnolle N, Riedel CA, Valitutti S, Kalergis A. T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2010;107(1):210-215.

117
Deletion Of A Prophage-Like Element Causes Attenuation Of Salmonella Enterica Serovar Enteritidis And Promotes Protective Immunity
Autor(es): Araya D, Quiroz T, Tobar H, Lizana R, Quezada C, Santiviago C, Riedel C, Kalergis A, Bueno S
Año: 2010.28:5458-5466.
Ref: Araya D, Quiroz T, Tobar H, Lizana R, Quezada C, Santiviago C, Riedel C, Kalergis A, Bueno S. Deletion of a prophage-like element causes attenuation of Salmonella enterica serovar Enteritidis and promotes protective immunity. Vaccine. 2010;28(33):5458-5466.

118
Gap Junctions At The Dendritic Cell-T Cell Interface Are Key Elements For Antigen-Dependent T Cell Activation
Autor(es): Elgueta R, Tobar Ja, Shoji Kf, De Calisto J, Kalergis Am, Bono Mr, Rosemblatt M, Saez Jc
Año: 2009.183:277-284.
Ref: Elgueta R, Tobar JA, Shoji KF, De Calisto J, Kalergis AM, Bono MR, Rosemblatt M, Sáez JC. Gap Junctions at the Dendritic Cell-T Cell Interface Are Key Elements for Antigen-Dependent T Cell Activation. Journal Of Immunology. 2009;183(1):277-284.

119
The Duration Of Tcr/pmhc Interactions Regulates Ctl Effector Function And Tumor-Killing Capacity
Autor(es): Riquelme E, Carreno Lj, Gonzalez Pa, Kalergis Am
Año: 2009.39:2259-2269.
Ref: Riquelme E, Carreño LJ, González PA, Kalergis AM. The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity. European Journal Of Immunology. 2009;39(8):2259-2269.

120
Primary Aldosteronism Can Alter Peripheral Levels Of Transforming Growth Factor Beta And Tumor Necrosis Factor Alpha
Autor(es): Carvajal Ca, Herrada Aa, Castillo Cr, Contreras Fj, Stehr Cb, Mosso Lm, Kalergis Am, Fardella Ce
Año: 2009.32:759-765.
Ref: Carvajal CA, Herrada AA, Castillo CR, Contreras FJ, Stehr CB, Mosso LM, Kalergis AM, Fardella CE. Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. Journal Of Endocrinological Investigation. 2009;32(9):759-765.

121
Altered Chemokine Receptor Expression In Papillary Thyroid Cancer
Autor(es): Gonzalez He, Leiva A, Tobar H, Boehmwald K, Tapia G, Torres J, Mosso L, Bueno S, Gonzalez P, Kalergis Am, Riedel Ca
Año: 2009.19:957-965.0
Ref: González HE, Leiva A, Tobar H, Boehmwald K, Tapia G, Torres J, Mosso L, Bueno S, González P, Kalergis AM, Riedel CA. Altered Chemokine Receptor Expression in Papillary Thyroid Cancer. Thyroid. 2009;19(9):957-965.

122
Use Of Genetically Modified Bacteria To Modulate Adaptive Immunity
Autor(es): Bueno Sm, Gonzalez Pa, Kalergis Am
Año: 2009.9:171-184.
Ref: Bueno SM, González PA, Kalergis AM. Use of Genetically Modified Bacteria to Modulate Adaptive Immunity. Current Gene Therapy. 2009;9(3):171-184.

123
Impairment Of T Cell Immunity By The Respiratory Syncytial Virus: Targeting Virulence Mechanisms For Therapy And Prophylaxis
Autor(es): Gonzalez Pa, Bueno Sm, Riedel Ca, Kalergis Am
Año: 2009.16:4609-4625.
Ref: González PA, Bueno SM, Riedel CA, Kalergis AM. Impairment of T Cell Immunity by the Respiratory Syncytial Virus: Targeting Virulence Mechanisms for Therapy and Prophylaxis. Current Medicinal Chemistry. 2009;16(34):4609-4625.

124
Modulation Of Nuclear Factor-Kappa B Activity Can Influence The Susceptibility To Systemic Lupus Erythematosus
Autor(es): Kalergis Am, Iruretagoyena Mi, Barrientos Mj, Gonzalez Pa, Herrada Aa, Leiva Ed, Gutierrez Ma, Riedel Ca, Bueno Sm, Iacobelli Sh
Año: 2009.128:e306-e314.
Ref: Kalergis AM, Iruretagoyena MI, Barrientos MJ, González PA, Herrada AA, Leiva ED, Gutiérrez MA, Riedel CA, Bueno SM, Iacobelli SH. Modulation of nuclear factor-kappa B activity can influence the susceptibility to systemic lupus erythematosus. Immunology. 2009;128(1):e306-e314.

125
Disease Activity In Systemic Lupus Erythematosus Is Associated With An Altered Expression Of Low-Affinity Fc Gamma Receptors And Costimulatory Molecules On Dendritic Cells
Autor(es): Carreno Lj, Pacheco R, Gutierrez Ma, Jacobelli S, Kalergis Am
Año: 2009.128:334-341.
Ref: Carreño LJ, Pacheco R, Gutiérrez MA, Jacobelli S, Kalergis AM. Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fc gamma receptors and costimulatory molecules on dendritic cells. Immunology. 2009;128(3):334-341.

126
Respiratory Syncytial Virus Impairs T Cell Activation By Preventing Synapse Assembly With Dendritic Cells
Autor(es): Gonzalez P, Prado C, Leiva E, Carreno L, Bueno S, Riedel C, Kalergis A
Año: 2008.105:14999-15004.
Ref: González P, Prado C, Leiva E, Carreño L, Bueno S, Riedel C, Kalergis A. Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2008;105(39):14999-15004.

127
Protective T Cell Immunity Against Respiratory Syncytial Virus Is Efficiently Induced By Recombinant Bcg
Autor(es): Bueno S, Gonzalez P, Cautivo K, Mora J, Leiva E, Tobar H, Fennelly G, Eugenin E, Jacobs W, Riedel C, Kalergis A
Año: 2008.105:20822-20827.
Ref: Bueno S, González P, Cautivo K, Mora J, Leiva E, Tobar H, Fennelly G, Eugenin E, Jacobs W, Riedel C, Kalergis A. Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2008;105(52):20822-20827.

128
The Capacity Of Salmonella To Survive Inside Dendritic Cells And Prevent Antigen Presentation To T Cells Is Host Specific
Autor(es): Bueno S, Gonzalez P, Carreno L, Tobar J, Mora G, Pereda C, Salazar-Onfray F, Kalergis A
Año: 2008.124:522-533.
Ref: Bueno S, González P, Carreño L, Tobar J, Mora G, Pereda C, Salazar-Onfray F, Kalergis A. The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific. Immunology. 2008;124(4):522-533.

129
Immunology South Of The Equator In The Americas
Autor(es): Rabinovich Ga , Kalergis Am , Zwirner Nw , Savino W
Año: 2008.9:1087-1090.
Ref: Rabinovich GA , Kalergis AM , Zwirner NW , Savino W . Immunology south of the equator in the Americas. Nature Immunology. 2008;9(10):1087-1090.

130
Activating And Inhibitory Fc Gamma Receptors Can Differentially Modulate T Cell-Mediated Autoimmunity
Autor(es): Iruretagoyena M, Riedel C, Leiva E, Gutierrez M, Iacobelli S, Kalergis A
Año: 2008.38:2241-2250.
Ref: Iruretagoyena M, Riedel C, Leiva E, Gutiérrez M, Iacobelli S, Kalergis A. Activating and inhibitory Fc gamma receptors can differentially modulate T cell-mediated autoimmunity. European Journal Of Immunology. 2008;38(8):2241-2250.

131
A Novel Adrenocorticotropin Receptor Mutation Alters Its Structure And Function, Causing Familial Glucocorticoid Deficiency
Autor(es): Artigas R, Gonzalez A, Riquelme E, Carvajal C, Cattani A, Martinez-Aguayo A, Kalergis A, Perez-Acle T, Fardella C
Año: 2008.93:3097-3105.
Ref: Artigas R, González A, Riquelme E, Carvajal C, Cattani A, Martínez-Aguayo A, Kalergis A, Pérez-Acle T, Fardella C. A novel adrenocorticotropin receptor mutation alters its structure and function, causing familial glucocorticoid deficiency. Journal Of Clinical Endocrinology And Metabolism. 2008;93(8):3097-3105.

132
Maternal Hypothyroxinemia Impairs Spatial Learning And Synaptic Nature And Function In The Offspring
Autor(es): Opazo M, Gianini A, Pancetti F, Azkcona G, Alarcon L, Lizana R, Noches V, Gonzalez P, Porto M, Mora S, Rosenthal D, Eugenin E, Naranjo D, Bueno S, Kalergis A, Riedel C
Año: 2008.149:5097-5106.
Ref: Opazo M, Gianini A, Pancetti F, Azkcona G, Alarcón L, Lizana R, Noches V, González P, Porto M, Mora S, Rosenthal D, Eugenin E, Naranjo D, Bueno S, Kalergis A, Riedel C. Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology. 2008;149(10):5097-5106.

133
Host Immunity During Rsv Pathogenesis
Autor(es): Bueno Sm,, Gonzalez, Pacheco, Cautivo, Tobar, Mora, Jimenez, Kalergis, Riedel
Año: 2008.8:1320-1329.
Ref: Bueno SM,, Gonzalez, Pacheco, Cautivo, Tobar, Mora, Jimenez, Kalergis, Riedel. Host Immunity During RSV Pathogenesis. International Immunopharmacology. 2008;8(10):1320-1329.

134
Injury Of Skeletal Muscle And Specific Cytokines Induce The Expression Of Gap Junction Channels In Mouse Dendritic Cells
Autor(es): Corvalan L, Araya R, Branes M, Saez P, Kalergis A, Tobar J, Theis M, Willecke K, Saez J
Año: 2007.211:649-660.
Ref: Corvalán L, Araya R, Branes M, Sáez P, Kalergis A, Tobar J, Theis M, Willecke K, Saez J. Injury of skeletal muscle and specific cytokines induce the expression of gap junction channels in mouse dendritic cells. Journal Of Cellular Physiology. 2007;211(3):649-660.

135
Melanocortin 1 Receptor Is Expressed By Uveal Malignant Melanoma And Can Be Considered A New Target For Diagnosis And Immunotherapy
Autor(es): Lopez M, Pereda C, Ramirez M, Mendoza-Naranjo A, Serrano A, Ferreira A, Poblete R, Kalergis A, Kiessling R, Salazar-Onfray F
Año: 2007.48:1219-1227.
Ref: López M, Pereda C, Ramírez M, Mendoza-Naranjo A, Serrano A, Ferreira A, Poblete R, Kalergis A, Kiessling R, Salazar-Onfray F. Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy. Investigative Ophthalmology & Visual Science. 2007;48(3):1219-1227.

136
Modulation Of Immunological Synapse By Membrane-Bound And Soluble Ligands
Autor(es): Gonzalez P, Carreno L, Figueroa C, Kalergis A
Año: 2007.18:19-31.
Ref: González P, Carreño L, Figueroa C, Kalergis A. Modulation of immunological synapse by membrane-bound and soluble ligands. Cytokine & Growth Factor Reviews. 2007;18(1-2):19-31.

137
Improving Translational Biomedical Research In Chile
Autor(es): Jimenez J, Kalergis A
Año: 2007.370:1598-1599.
Ref: Jiménez J, Kalergis A. Improving translational biomedical research in Chile. Lancet. 2007;370(9599):1598-1599.

138
A Possible Association Between Primary Aldosteronism And A Lower Beta-Cell Function
Autor(es): Mosso L, Carvajal C, Maiz A, Ortiz E, Castillo C, Artigas R, Fardella C
Año: 2007.25:2125-2130.
Ref: Mosso L, Carvajal C, Maiz A, Ortíz E, Castillo C, Artigas R, Fardella C. A possible association between primary aldosteronism and a lower beta-cell function. Journal Of Hypertension. 2007;25(10):2125-2130.

139
The Half-Life Of The T-Cell Receptor/peptide-Major Histocompatibility Complex Interaction Can Modulate T-Cell Activation In Response To Bacterial Challenge
Autor(es): Carreno L, Bueno S, Bull P, Nathenson S, Kalergis A
Año: 2007.121:227-237.
Ref: Carreño L, Bueno S, Bull P, Nathenson S, Kalergis A. The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology. 2007;121(2):227-237.

140
T Cell Immunity Evasion By Virulent Salmonella Enterica
Autor(es): Bueno S, Gonzalez P, Schwebach J, Kalergis A
Año: 2007.111:14-20.
Ref: Bueno S, González P, Schwebach J, Kalergis A. T cell immunity evasion by virulent Salmonella enterica. Immunology Letters. 2007;111(1):14-20.

141
A Polymorphic Gt Short Tandem Repeat Affecting Beta-Enac Mrha Expression Is Associated With Low Renin Essential Hypertension
Autor(es): Gonzalez A, Carvajal C, Riquelme E, Krall P, Munoz C, Mosso L, Kalergis A, Fardella C
Año: 2007.20:800-806.
Ref: González A, Carvajal C, Riquelme E, Krall P, Muñoz C, Mosso L, Kalergis A, Fardella C. A polymorphic GT short tandem repeat affecting beta-ENaC mRHA expression is associated with low renin essential hypertension. American Journal Of Hypertension. 2007;20(7):800-806.

142
Immune Complex-Induced Enhancement Of Bacterial Antigen Presentation Requires Fc Gamma Receptor Iii Expression On Dendritic Cells
Autor(es): Herrada A, Contreras F, Tobar J, Pacheco R, Kalergis A
Año: 2007.104:13402-13407.
Ref: Herrada A, Contreras F, Tobar J, Pacheco R, Kalergis A. Immune complex-induced enhancement of bacterial antigen presentation requires Fc gamma Receptor III expression on dendritic cells. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2007;104(33):13402-13407.

143
Short-Term Lipopolysaccharide Stimulation Induces Differentiation Of Murine Bone Marrow-Derived Dentritic Cells Into Tolerogenic Phenotype
Autor(es): Salazar L, Aravena O, Contreras-Levicoy J, Pesce B, Catalan D, Zuniga R, Iruretagoyena M, Kalergis A, Aguillon J
Año: 2007.18:78-85.
Ref: Salazar L, Aravena O, Contreras-Levicoy J, Pesce B, Catalán D, Zúñiga R, Iruretagoyena M, Kalergis A, Aguillon J. Short-term lipopolysaccharide stimulation induces differentiation of murine bone marrow-derived dentritic cells into tolerogenic phenotype. European Cytokine Network. 2007;18(2):78-85.

144
The Dendritic Cell-T Cell Synapse As A Determinant Of Autoimmune Pathogenesis
Autor(es): Iruretagoyena M, Wiesendanger M, Kalergis A
Año: 2006.12:131-147.
Ref: Iruretagoyena M, Wiesendanger M, Kalergis A. The Dendritic Cell-T Cell Synapse As a Determinant of Autoimmune Pathogenesis. Current Pharmaceutical Design. 2006;12(2):131-147.

145
Modulation Of T Cell Function By Tcr/pmhc Binding Kinetics
Autor(es): Carreno L, Gonzalez P, Kalergis A
Año: 2006.211:47-64.
Ref: Carreño L, González P, Kalergis A. Modulation of T Cell Function by Tcr/Pmhc Binding Kinetics. Immunobiology. 2006;211(1-2):47-64.

146
Inhibition Of Nuclear Factor-Kappa B Enhances The Capacity Of Immature Dendritic Cells To Induce Antigen-Specific Tolerance In Experimental Autoimmune Encephalomyelitis
Autor(es): Iruretagoyena M, Sepulveda S, Lezana J, Hermoso M, Bronfman M, Gutierrez M, Jacobelli S, Kalergis A
Año: 2006.318:59-67.
Ref: Iruretagoyena M, Sepúlveda S, Lezana J, Hermoso M, Bronfman M, Gutiérrez M, Jacobelli S, Kalergis A. Inhibition of Nuclear Factor-Kappa B Enhances the Capacity of Immature Dendritic Cells to Induce Antigen-Specific Tolerance in Experimental Autoimmune Encephalomyelitis. Journal Of Pharmacology And Experimental Therapeutics. 2006;318(1):59-67.

147
Virulent Salmonella Enterica Serovar Typhimurium Evades Adaptive Immunity By Preventing Dendritic Cells From Activating T Cells
Autor(es): Tobar J, Carreno L, Bueno S, Gonzalez P, Mora J, Quezada S, Kalergis A
Año: 2006.74:6438-6448.
Ref: Tobar J, Carreño L, Bueno S, González P, Mora J, Quezada S, Kalergis A. Virulent Salmonella Enterica Serovar Typhimurium Evades Adaptive Immunity by Preventing Dendritic Cells From Activating T Cells. Infection And Immunity. 2006;74(11):6438-6448.

148
Molecular Interactions Between Dendritic Cells And Salmonella: Escape From Adaptive Immunity And Implications On Pathogenesis
Autor(es): Bueno S, Tobar J, Iruretagoyena M, Kalergis A
Año: 2005.25:389-403.
Ref: Bueno S, Tobar J, Iruretagoyena M, Kalergis A. Molecular Interactions Between Dendritic Cells and Salmonella: Escape From Adaptive Immunity and Implications on Pathogenesis. Critical Reviews In Immunology. 2005;25(5):389-403.

149
T Cell Receptor Binding Kinetics Required For T Cell Activation Depend On The Density Of Cognate Ligand On The Antigen-Presenting Cell
Autor(es): Gonzalez P, Carreno L, Coombs D, Mora J, Palmieri E, Goldstein B, Nathenson S, Kalergis A
Año: 2005.102:4824-4829.
Ref: González P, Carreño L, Coombs D, Mora J, Palmieri E, Goldstein B, Nathenson S, Kalergis A. T Cell Receptor Binding Kinetics Required for T Cell Activation Depend on the Density of Cognate Ligand on the Antigen-Presenting Cell. Proceedings Of The National Academy Of Sciences Of The United States Of Ame. 2005;102(13):4824-4829.

150
Andrographolide Interferes With T Cell Activation And Reduces Experimental Autoimmune Encephalomyelitis In The Mouse
Autor(es): Iruretagoyena M, Tobar J, Gonzalez P, Sepulveda S, Figueroa C, Burgos R, Hancke J, Kalergis A
Año: 2005.312:366-372.
Ref: Iruretagoyena M, Tobar J, González P, Sepúlveda S, Figueroa C, Burgos R, Hancke J, Kalergis A. Andrographolide Interferes With T Cell Activation and Reduces Experimental Autoimmune Encephalomyelitis in the Mouse. Journal Of Pharmacology And Experimental Therapeutics. 2005;312(1):366-372.

151
Interaction At The Dendritic Cell/t-Cell Interface Define The Balance Between Immunity And Tolerance
Autor(es): Iruretagoyena M, Lezana M, Kalergis A
Año: 2005.32:373-383.
Ref: Iruretagoyena M, Lezana M, Kalergis A. Interaction At the Dendritic Cell/T-Cell Interface Define the Balance Between Immunity and Tolerance. Transfusion Medicine And Hemotherapy. 2005;32(6):373-383.

152
La Deteccion Antigeno-Especifica De Linfocitos T Y Sus Aplicaciones Clinicas
Autor(es): Kalergis A
Año: 2004.132:371-380.
Ref: Kalergis A. La Deteccion Antigeno-Especifica de Linfocitos T y Sus Aplicaciones Clinicas. Revista Medica De Chile. 2004;132(3):371-380.

153
[Clinical Applications Of Antigen-Specific Detection Of T Lymphocytes].
Autor(es): Kalergis Am, Fierro A, Figueroa C, Gonzalez Pa, Tobar Ja
Año: 2004.3:371-380.
Ref: Kalergis AM, Fierro A, Figueroa C, González PA, TOBAR JA. [Clinical applications of antigen-specific detection of T lymphocytes].. Revista Medica De Chile. 2004;3(132):371-380.

154
Salmonella Escape From Antigen Presentation Can Be Overcome By Targeting Bacteria To Fcy Receptor On Dentritic Cells
Autor(es): Tobar J, Gonzalez P, Kalergis A
Año: 2004.173:4058-4065.
Ref: Tobar J, González P, Kalergis A. Salmonella Escape From Antigen Presentation Can Be Overcome by Targeting Bacteria to Fcy Receptor on Dentritic Cells. Journal Of Immunology. 2004;173(6):4058-4065.

155
Modulation Of T Cell Immunity By Tcr/pmhc Dwell Time And Activating/inhibitory Receptor Pairs On The Antigen-Presenting Cell
Autor(es): Kalergis A
Año: 2003.9:233-244.
Ref: Kalergis A. Modulation of T Cell Immunity by Tcr/Pmhc Dwell Time and Activating/Inhibitory Receptor Pairs on the Antigen-Presenting Cell. Current Pharmaceutical Design. 2003;9(3):233-244.

156
Cd8+ T Cells Are The Effectors Of The Contact Dermatitis Induced By Urushiol In Mice And Are Regulated By Cd4+ T Cells
Autor(es): Lopez C, Kalergis A, Becker M, Garbarino J, De Ioannes A
Año: 1998.117:194-201.
Ref: López C, Kalergis A, Becker M, Garbarino J, De Ioannes A. Cd8+ T Cells Are the Effectors of the Contact Dermatitis Induced by Urushiol in Mice and Are Regulated by Cd4+ T Cells. International Archives Of Allergy And Immunology. 1998;117(3):194-201.

157
Modulation Of Fatty Aced Oxidation Alters Contact Hypersensitivity To Urushiols: Role Of Aliphatic Chain B-Oxidation In Processing And Activation Of Urushiols
Autor(es): Kalergis A, Lopez C, Becker M, Diaz M, Sein J, Garbarino J, De Ioannes A
Año: 1997.108:57-61.
Ref: Kalergis A, López C, Becker M, Díaz M, Sein J, Garbarino J, De Ioannes A. Modulation of Fatty Aced Oxidation Alters Contact Hypersensitivity to Urushiols: Role of Aliphatic Chain B-Oxidation in Processing and Activation of Urushiols. Journal Of Investigative Dermatology. 1997;108(1):57-61.



Libros y Capitulos de Libros


Herpesviridae, Immune Evasion By Herpes Simplex Viruses Http://www.intechopen.com/books/herpesviridae/immune-Evasion-By-Herpes-Simplex-Viruses
Autor(es): Angello R. Retamal-Diaz, Eduardo Tognarelli, Alexis M. Kalergis, Susan M. Bueno, Pablo A. Gonzalez
Año: 2016:-42.
Ref: Angello R. Retamal-Díaz, Eduardo Tognarelli, Alexis M. Kalergis, Susan M. Bueno, Pablo A. González. Herpesviridae, Immune Evasion by Herpes Simplex Viruses http://www.intechopen.com/books/herpesviridae/immune-evasion-by-herpes-simplex-viruses. 2016. Jozsef Ongradi,editors. Croacia: INTECH; 2016.

Immune Evasion By Herpes Simplex Viruses
Autor(es): Retamal-Diaz A, Tognarelli E, Kalergis Am, Bueno Sm, Gonzalez Pa
Año: 2016:105-146.
Ref: Retamal-Diaz A, Tognarelli E, Kalergis AM, Bueno SM, Gonzalez PA. Immune Evasion by Herpes Simplex Viruses. In: Jozsef Ongradi,editors. Herpesviridae. Croacia: INTECH; 2016. p. 105-146.

Immunoregulatory Properties Of Heme Oxygenase-1
Autor(es): Kalergis, Am
Año: 2011:247-268.
Ref: Kalergis, AM. Immunoregulatory Properties of Heme Oxygenase-1. In: Maria Cristina Cuturi, Ignacio Anegon,editors. Suppression and Regulation of Immune Responses. Nantes, France: Humana Press; 2011. p. 247-268.

Induction Of Tolerogenic Dendritic Cells By Nf-Kb Blockade And Fcy Receptor Modulation
Autor(es): Alexis M. Kalergis
Año: 2011:339-353.
Ref: Alexis M. Kalergis. Induction of Tolerogenic Dendritic Cells by NF-kB Blockade and Fcy Receptor Modulation. In: Maria Cristina Cuturi, Ignacio Anegon,editors. Suppression and Regulation of Immune Responses. Nantes, France: Humana Press; 2011. p. 339-353.